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Biowhittaker Molecular Applications, Inc.

Hugh W White

Richard B Provonchee

Douglas H Robinson

Noriko Kusukawa

Thomas M Stein

Minjie Wu

The present invention discloses the use of quaternary compounds as stabilizing agents for highly-sensitive fluorescent nucleic acid stains in aqueous solvents, their use in gels to give increased usable shelf life, and in compositions of solvents, providing ready-to-use stain solutions.

Stabilization of highly sensitive nucleic acid stains in aqueous solutions

An anchoring device to be placed atop a slab of electrophoresis gel in a submerged electrophoresis process chamber includes a planar frame member shaped and sized to distribute weight evenly across the gel slab, particularly having a width dimension generally the same as the slab, and a plurality of legs spaced evenly around the frame. The legs have a length sufficient to raise the frame above the level of buffer liquid in process chamber, and have a blunt bottom surface in contact with the gel slab. The weight of the device and the even distribution of that weight is sufficient to anchor the gel slab and keep it submerged in the buffer liquid in the electrophoresis process chamber while making minimal contact with the slab and not distorting the electrical field through the gel, and without penetrating or lacerating the slab. The frame encloses one or more open window areas above the sample wells in the gel slab to permit easy access to load biological samples.

Anchor for electrophoresis gel

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Camden, ME, United States of America

Hugh W White