Firmenich Sa

Huey-Ling Kao

Stefan Alexander Ruider

Anthony Alexander Birkbeck

Julien Coulomb

Patrick Pfister

Matthew E Rogers

Steven Williams

Gary Marr

Ben Smith

Zhenan Wu

Mushhood Sheikh

Claude Ayome Abibi

The various aspects presented herein relate to the perfumery industry. More particularly, the various aspects presented herein relate to malodor counteracting compositions and/or ingredients, methods for counteracting malodors, as well as to the perfumed articles or perfuming compositions comprising as an active ingredient, at least one compound selected from the group consisting of: a compound of Formula (I), a compound of Formula (II), a compound of Formula (III), a compound of Formula (IV), and mixtures thereof.

Spiro compounds as malodor counteracting ingredients

Provided herein are polypeptides that bind to the malodour-causing substance DMTS. Also provided are nucleic acid sequences that encode for the polypeptides. Further provided herein is a method for identifying a compound that binds, suppresses, blocks, inhibits, and/or modulates the activity of one or more olfactory receptor that is activated by the malodor-causing substance DMTS comprising a) contacting the receptor, or a chimera or fragment thereof with a compound and b) determining whether the compound has an effect on the activity of the receptor. Further provided is an expression vector comprising the nucleic acid encoding the polypeptides described as well as a non-human organism or a host cell modified to express a receptor that is activated by DMTS. Also provided is the use of the polypeptides for identifying malodor modulating compounds.

Method of identifying malodor modulating compounds

The various aspects presented herein relate to the perfumery industry. More particularly, the various aspects presented herein relate to the use of volatile compositions to limit, decrease or eliminate the perception of malodor. Such compositions include at least one malodor antagonist optionally combined with perfuming ingredients. Such compositions, their use in combination with delivery systems and their applications in consumer products are also objects of the present disclosure.

Use of volatile compositions to limit or eliminate the perception of malodor

The various aspects presented herein relate to the perfumery industry. More particularly, the various aspects presented herein relate to malodor counteracting compositions and/or ingredients, methods for counteracting malodors, as well as to the perfumed articles or perfuming compositions comprising as an active ingredient, at least one compound selected 5 from the group consisting of: 1-(2-methyl-4-tricyclo[5.2.1.0]decanyl)ethyl acetate, 1-(2,4-di-methyl-4-tricyclo[5.2.1.0]decanyl)ethyl acetate, 1-((1R,3S,3aS,6S)-1,2,3-trimethyloctahydro-3a,6-methanoinden-1-yl)ethan-1-one, 1-(2,4-dimethyl-4-tricyclo[5.2.1.0{circumflex over (&#x2003;)}{1,5}]decanyl)ethanone, 2,3,4-trimethyltricyclo[5.2.1.0{circumflex over (&#x2003;)}{1,5}]decane-4-carbaldehyde, (2,3,4-trimethyl-4-tricyclo[5.2.1.0{circumflex over (&#x2003;)}{1,5}]decanyl)methyl acetate, 1-((3aS,6S)-10 2,3-dimethyloctahydro-3a,6-methanoinden-1-yl)ethan-1-one oxime, 1,3-dimethyloctahydro-3a,6-methanoindene-1-carbaldehyde oxime, &#x2dc;{N}-[1-[(1&#x2dc;{R},7&#x2dc;{R})-2,3,4-trimethyl-4-tricyclo[5.2.1.0]decanyl]ethylidene]hydroxylamine, (+&#x2212;)-1-(2,4-dimethyltricyclo[5.2.1.0]dec-4-yl) ethanone, (+&#x2212;)-1-(2,4-dimethyltricyclo[5.2.1.0&#x2dc;1.5&#x2dc;]dec-4-yl) ethyl acetate, 1-[(1RS,2RS,4SR,7RS)-2,3,4-trimethyltricyclo[5.2.1.01.&#x2dc;]dec-4-yl) 15 ethanone, (E/Z)-1-[(1RS,7RS)-2,3-dimethyltricyclo[5.2.1.0]dec-4-yl) ethanone oxime, (E/Z)-1-[(1S,7S)-2,3,4-trimethyltricyclo[5.2.1.0&#x2dc;1.5&#x2dc;]dec-4-yl) ethanone oxime, (E/Z)-1-((3aS,6S)-1,2,3-trimethyloctahydro-3a,6-methanoinden-1-yl)ethanone oxime, (+&#x2212;)-1-(3-methyloctahydro-3a,6-methanoinden-1-yl)ethyl acetate, and mixtures thereof.

Malodor counteracting ingredients

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Plainsboro, NJ, United States of America

Huey-Ling Kao