Npbi Nederlands Produktielaboratorium Voor Bloedtransfusieapparatuur En

The Secretary of State for Defence in Her Britannic Majesty's Government

Hubertus E Hilbrink

Johannes Van Der Heiden

Frank T Biekart

Michael J Thomas

Susan H Bell

Joseph Goertz

Freezing bags

A syringe assembly having a syringe has an outlet opening and a tube having an inner end hermetically sealed over the outlet opening and an outer end. Thus any contents of the syringe can flow unimpeded via the outlet into the tube and vice versa. A seal hermetically closes the outer end of the tube. Such a syringe assembly is filled from a medical-liquid-holding container also having an outlet opening provided with a respective such tube whose outer end is similarly sealed. The syringe is filled by first unsealing and joining the outer ends of the tubes to each other in a sterile docking procedure, then aspirating the medicament through the unsealed and joined ends and resealing the tubes together, and finally cutting the tubes apart where they are sealed together to form two new seals on the tube outer ends.

Closed syringe-filling system

A clamp for blocking flow through a flexible hose is formed of a one-piece L-shaped body of rigid material having a short leg formed with a generally circular throughgoing hole through which the hose can pass loosely enough for flow through the tube and a long leg formed with a throughgoing slot narrow enough that when the tube passes through it flow through the tube is blocked. The hole and slot communicate with and open into each other at a corner where the two legs join. The clamp is formed with a generally cylindrical passage forming the circular hole. This passage extends along an axis generally parallel to the long leg of the clamp. The cylindrical passage is formed by a pair of like part-cylindrical surfaces having a common centerline and each in turn formed on a wing-like side part of the clamp.

One-piece slidable hose clamp

An aseptic solution for IV administration is prepard by thrusting a drug vial over a needle of a connector having a valve provided with a sterilizing air filter. In a first position of the valve, the communication to the IV container is blocked, but the vial is connected to the atmosphere through the sterilizing air filter to allow equalization of the atmospheric pressure with the pressure in the vial. In the second position, the communication with the filter is cutoff and the vial is connected to the IV container to allow IV solution to enter the vial and solution to be transferred between the vial and the IV container. In a final position, the ports of the valve are all blocked to close off the vial in which the sterile air is now trapped so that loss of the IV solution into the vial will be prevented.

Method of and apparatus for administering medicament to a patient

Growing community of inventors

Emmen, Netherlands

Hubertus E Hilbrink