Hoechst Aktiengesellschaft

Hoecht Ag

Verla-pharm Arzneimittelfabrik Apotheker H.j.v. Ehrlich Gmbh & Co. Kg

Coventya S.p.a.

Hubert Schmidbaur

Hans-Jurgen Fuller

Joachim Helbig

Jean-Jacques Duprat

Hans-Heinz Karsch

Graham Bowmaker

Oswald Gasser

Cornelia Dorzbach

Ester Falletta

Davide Rossi

Novel bis-phosphonium salts of the general formula ##STR1## in which R.sup.1 stands for a straight or branched alkyl group having from 1 to 12 carbon atoms,

Bis-phosphonium salts and process for making them

The invention concerns a novel process for the production of a complex cound comprising an amino-dicarboxylic acid ion component, a bivalent metal ion component, and a halogen ion component, which comprises the step of reacting together in an aqueous medium an amino-dicarboxylic acid compound, a bivalent metal compound, and a halogen compound, the proportions of said compounds being chosen so that one of each of said ion components is comprised in the aqueous medium, the bivalent metal compound being selected from the oxide, hydroxide, carbonate or a halide of the bivalent metal, and the halogen compound being said halide of the bivalent metal or a hydrogen halide. Certain of the complexes are novel and find use in a variety of medical and veterinary fields.

Process for the production of amino-dicarboxylic acid-bivalent

Double ylide complexes of metals are made by reacting trimethylphosphin-imino-dimethyl-methylene phosphorane of the formula ##STR1## with one or more compounds of the metals nickel, palladium, platinum, gold, zinc, cadmium, aluminum, gallium, indium, thallium, magnesium or lithium. The novel double ylide complexes comprise various metal-bis[nitrido-bis(dimethylphosphonium methylides)], dimethyl-metal[nitrido-bis(dimethylphosphonium methylides)], and lithium-[nitrido-bis(dimethylphosphonium methylide)].

Double ylide complexes of metals and process for making them

Novel chemical compounds which comprise tetramethyldiphosphinomethane of the formula:

Process for making tetramethyldiphosphinomethane

Double-ylide metal complexes are made. To this end, one or more bis-�methyl-(diorganyl)-phosphoranylidene!-methanes of the general formula

Double-ylide metal complexes

Trimethyl phosphinimino dimethyl methylene phosphorane of the formula: ##STR1## which is a novel chemical compound is produced. To this end, a tetramethyl phosphonium halide is reacted with 1.1 to 1.5 times the molar quantity of an alkali metal amide in an organic solvent, at 0.degree. to 35.degree. C, with the exclusion of air and moisture, and over a period of 24 to 72 hours. The reaction mixture is freed from residue and subjected to fractional distillation.

Growing community of inventors

Garching, Germany

Hubert Schmidbaur