Cl Pharma Aktiengesellschaft

Chemisch Pharmazeutische Forschungsgesellschaft M.b.h.

Chemie Linz Aktiengesellschaft

Laevosan-Gesellschaft Mbh & Co. Kg Chemisch-Pharmazeutische Industrie

Hubert P Ferber

Dieter Binder

Franz Rovenszky

Josef Weinberger

Ernst Nitsch

Franz Rovensky

Karsten Schror

Siegfried Muhlbock

Norman Brunner

Sulphamoylathiophenes of the formula ##STR1## in which Y denotes O or S,

Sulphamoylthiophenes, a process for their preparation

Thienopyran derivatives of the general formula ##STR1## in which the radial ##STR2## denotes one of the formulae ##STR3## R denotes hydrogen or a radical --CN, --CHO, --CH.dbd.NOH, --CONH.sub.2 or --COOR.sub.1,

Thienopyran derivatives, their use for treating hypertension and asthma

The invention relates to novel thieno-(3',4'-4,5)imidazo(2,1-b)thiazole derivatives of the formula ##STR1## in which R.sub.1 denotes hydrogen, halogen or CF.sub.3 and

Thieno (3',4'-4,5)imidazo(2,1-b)thiazole derivatives, a process for

The invention relates to new enol ethers of 6-chloro-4-hydroxy-2-methyl-N-(2-pyridyl)-2H-thieno(2,3-e)-1,2- thiazine-3-carboxamide 1,1-dioxide of the formula ##STR1## in which R denotes (C.sub.1 -C.sub.6)-alkyl, (C.sub.5 -C.sub.7)-cycloalkyl or benzyl, and a process for their preparation. The new compounds have an antiinflammatory activity and are suitable for the treatment of rheumatism.

Enol ethers of

The invention relates to novel 2-thienyloxyacetic acid derivatives of the general formula ##STR1## in which R denotes a phenyl or thienyl group which is optionally mono- or polysubstituted by halogen, trifluoromethyl or C.sub.1 -C.sub.4 alkyl, and pharmaceutically usable salts thereof, a process for the preparation of these compounds and their use for the treatment of thromboses, inflammations, high blood pressure, apoplexy and angina pectoris.

Novel 2-thienyloxyacetic acid derivatives, a process for their

Substituted isoxazoles of the formula ##STR1## in which R.sub.1 denotes C.sub.1 -C.sub.4 alkyl, R.sub.2 denotes hydrogen, C.sub.1 -C.sub.4 alkyl chlorine or bromine, R.sub.3 and R.sub.4, which are the same or different are hydrogen or C.sub.1 -C.sub.4 alkyl, but not both hydrogen and n denotes the interger 6, 7, or 8. The novel ocmpounds have a pronounced antiviral action and can be employed for the treatment and prophylaxis of virus diseases.

Isoxazole derivatives with antiviral activities and pharmaceutical

The invention relates to novel derivatives of 4,5-dihydrooxazoles of the formula ##STR1## in which A denotes --CH.dbd.CH-- or --S--,

Derivatives of pyridylsulfinyl(benz-or thieno-)imidazoles and their use

The invention relates to new nitrogen-arylmethoxy-thiophene derivatives of the formula I ##STR1## wherein the R--CH.sub.2 --O-group is in position 4 or 5 of the thiophene ring, R denotes a 2-pyridinyl- or 2-quinolinyl group and R.sub.1 denotes a --COO-lower alkyl-, --CO--(CH.sub.2)n--CH.sub.3 or --CH(OH)--(CH.sub.2).sub.n --CH.sub.3 group, wherein n represents an integer from 2 to 6, and their hydrates and/or their pharmaceutically acceptable acid addition salts, a process for their preparation and pharmaceutical products containing these compounds. The new compounds and their salts have useful pharmacological properties. They can be used as active compounds for medicaments for the treatment and prevention of diseases, caused by a disturbance in arachidonic acid metabolism.

Nitrogen-arylmethoxy-thiophene derivatives and acid addition salts

The present invention provides a process for the preparation of a plasma based on starch by the hydrolytic decomposition of an amylopectin-rich starch to a definite molecular weight and partial etherification to a definite substitution before or after the hydrolysis, wherein the hydrolytic decomposition is carried out at least partly with .alpha.-amylase, .beta.-amylase or pullulanase.

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Ansfelden, Austria

Hubert P Ferber