Boehringer Ingelheim International Gmbh

Hubert Kunze

Johannes Geser

Gilbert Wuttke

Elmar Mock

Burkhard Metzger

Antonino Lanci

Ralf Thoemmes

Andre Klopfenstein

Achim Moser

Bernd Zierenberg

Michael Spallek

Herbert Wachtel

Andreas Fiol

Michael Schyra

Michael Krueger

Guido Schmiedel

Jens Besseler

Heinrich Kladders

Matthias Hausmann

Georg Boeck

Christoph Dworzak

Markus Mast

Christian Golberg

Birgit Westmeier

Stefan Kaulmann

Dieter Hochrainer

Florian Witte

André Klopfenstein

Klaus Noehl

Carsten Henning

Josef Eckert

Antonio Lanci

Ralf Thömmes

Christian Goldberg

Burkhard P Metzger

Johannnes Geser

A nebulizer having an insertable container and a monitoring device for counting actuations of the nebulizer is proposed. The monitoring device is mounted in a detachable housing part and directly detects movements of container during a nebulizing process, an air supply current in the region of a mouthpiece, and/or the production of aerosol, in order to detect this as the actual dispensing of fluid and actuation of the nebulizer, while preferably the time of actuation of the nebulizer is additionally detected and stored. This allows better monitoring and guidance for the user.

Nebulizer

A medicine dispensation device, in particular a multi-dose powder inhalator, for the dispensing of individual doses of medicine that has a number of medicine chambers contained in a medicine magazine shaped like a continuous loop. The medicine chambers form groups in such a manner that a mouthpiece reaches the different groups by an essentially complete rotation of the medicine magazine. This enables several medicine chambers&#x2014;typically one, two or three&#x2014;to be situated between two successive intake positions, which allows for a high density of medicine chambers and thus creates an inhalation device, which can be handled comfortably even when containing a great number of individual doses.

Medicine dispensation device

An inhaler () is proposed (see FIG.), for the inhalation of a formulation () from capsules () that each contain one dose of the formulation. The capsules are preferably each emptied in a capsule chamber () by being set in motion by a stream of air flowing through the capsule chamber. The stream of air can be generated by the inhalation of a user or patient and/or can be generated actively generated by the inhaler. For simple handling, the inhaler has a means for, in particular, automatic filling, emptying and/or cleaning of the capsule chamber, if the latter is used more than once. Alternatively, the inhaler has a large number of capsule chambers that each preferably already contain a capsule and re preferably used just once.

Inhaler

A medicament dispensing device, a medicament magazine thereof, and a method of removing a medicament from the medicament magazine. The inhaler has a mouthpiece () and an air channel () connected thereto, as well as a medicament magazine with at least one medicament chamber containing a powdered medicament. A drive current is produced in the air channel, while a vacuum flow (') can be produced by the drive current and a constriction formed in the air channel. This narrowest part of the air channel that produces the vacuum flow is connected to a removal opening () which communicates with a control opening (), in order to form an emptying current through the control opening via the removal opening. In a preferred embodiment the at least one medicament chamber including the control opening, the removal opening and a fill opening are housing in the one-piece medicament magazine.

Medicament dispensing device, medicament magazine therefor and method of removing a medicament from a medicament chamber

An atomizer for a fluid, in particular, a fluid for medical aerosol therapy. In order to allow simplified operation and improved safety in use, the atomizer has a counter device for counting the number of operations of the atomizer and the number of containers inserted. The atomizer is locked against further operation and/or against removal of the current container or insertion of a new container, if a certain number of operations of the atomizer and/or a certain number of containers inserted has/have been reached or exceeded.

Atomizer

The invention is a medicament magazine having at least one medicament chamber for use in a powder inhaler, wherein the magazine is formed from two foil strips applied to one another and the at least one medicament chamber is formed between the foil strips as depicted in exemplary FIGS.and. The medicament chambers have an internal structure () which comprises in its interior a space for receiving a powdered medicament and stabilizes this inner space against external mechanical influences. In another embodiment in which the internal structure preferably also has a stabilizing function, the structure has means for opening one foil strip. In addition, the medicament chamber contains a retaining device which holds the internal structure on the medicament magazine after the medicament chamber has been opened.

Medicaments magazine for an inhaler, and a multi-dose powder inhaler

A nebuliser and a container in each case with an aeration device are proposed, the aeration device being designed for the direct aeration of a liquid space in the container. The container comprises a rigid, gas-tight outer case and a closure, which is opened by connecting or inserting a delivery element. A long storage life and long service life with low loss of fluid or solvent are thereby provided in the form of a simple and inexpensive construction.

Nebuliser and container

A nebulizer for a fluid and a container holding the fluid which is insertable in the nebulizer are proposed. To improve safety in use it is proposed that the nebulizer comprises first coding means and the container is associated with second coding means, so that the container can only be inserted in the nebulizer or used therewith if the codes match. Preferably, the code associated with the container comprises clear identification of the fluid contained in the container.

A nebulizer for a fluid, particularly for medicinal aerosol therapy. To allow easy operation, the nebulizer has a valve device, so that air supply openings in a mouthpiece can be blocked off to prevent backflow.

A nebulizer for a fluid having a pressure generator for conveying and nebulizing the fluid, particularly in the form of an inhaler, is proposed. To improve the user guidance it is envisaged that the nebulizer should have a signal device for generating at least one acoustic and/or vibratory signal, particularly during a nebulizing process.

Growing community of inventors

Dortmund, Germany

Hubert Kunze