Institute of Animal Husbandry and Veterinary Sciences, Hubei Academy of Agricultural Sciences

Huabin Shao

Rongrong Zhang

Yu Shang

Guoyuan Wen

Qingping Luo

Honglin Wang

Ling Luo

Li Li

Hongcai Wang

Tengfei Zhang

Wenting Zhang

Qin Lu

Jing Guo

Chen Chen

Jun Yang

Diyun Ai

A heat-resistant H1N1 subtype influenza virus mutant strain rPR8-HA-N5 has been preserved at China Center for Type Culture Collection, Wuhan University, Wuhan, China with the preservation number of CCTCC No. V202043.

Heat-resistant H1N1 subtype influenza virus mutant strain, preparation method and application thereof

A heat-resistant recombinant Newcastle Disease Virus vaccine strain rLS-tFib2-C capable of expressing truncated Fiber 2 protein of fowl adenovirus serotype 4 has been preserved at the China Center for Type Culture Collection, Wuhan University, Wuhan, China with the preservation number of CCTCC No. V202042.

Heat-resistant recombinant Newcastle Disease Virus vaccine strain capable of expressing truncated Fiber 2 protein of Fowl Adenovirus serotype 4, preparation method and application thereof

A heat-resistant NDV live vaccine vector system includes a transcription plasmid, three helper plasmids, and host cells. The transcription plasmid is constructed by through cloning complete genomic cDNA of a heat-resistant NDV vaccine strain to a pBR322 vector. The three helper plasmids are constructed by cloning sequences coding nucleoprotein (NP), phosphoprotein, large polymerase protein of a heat-resistant NDV vaccine strain respectively to pcDNA3.1 vectors. A recombinant NDV artificially obtained by cotransfacting host cells with the transcription plasmid and the three helper plasmids shows heat-resistance.

Heat-resistant newcastle disease virus live vaccine vector system and use thereof

Growing community of inventors

Wuhan, China

Huabin Shao