Shanghai Kexin Biotech Co., Ltd.

Hua Mao

Yue Zhang

Jun Bao

Pangke Yan

Feng Peng

Weina Situ

Jie Qian

Yongjun Han

Zhinan Shou

Hongbin Sun

Xiaofeng Zeng

Fei Xiang

Xuanmiao Zhang

Juanjuan Deng

The present application provides compositions and methods useful for detecting and monitoring autoimmune diseases in a human subject. The methods comprise providing a moesin fragment for binding to an anti-moesin autoantibody and contacting the moesin fragment with a sample obtained from the human subject. The moesin fragment comprises the entire N-terminal FERM domain of a human moesin protein. The human subject has or is suspected of having an autoimmune disease such as connective tissue disease, systemic sclerosis, Sjogren's syndrome, or systemic lupus erythematosus.

Moesin fragments and uses thereof

The present application provides compositions and methods useful for detecting and monitoring acquired aplastic anemia.

Moesin fragments associated with aplastic anemia

The present application provides compositions and methods useful for treating and diagnosing diseases and disorders associated with moesin activation.

Moesin modulators and uses thereof

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Shanghai, China

Hua Mao