Mackay Memorial Hospital

Chung Yuan Christian University

Goldred Nanobiotech Co., Ltd.

Hsueh-Hsiao Wang

Hung-I Yeh

Cheng-An J Lin

Walter H Chang

Hong-Shong Chang

Disclosed herein is a method for treating an inflammatory disease in a subject, including administering to the subject a therapeutically effective amount of a dihydrolipoic acid (DHLA) coated gold nanocluster about 0.1 to 20 nm in diameter. Also disclosed is a method for reducing the expression of a pro-inflammatory molecule in a cultured cell, including contacting the cultured cell with the said DHLA coated gold nanocluster. Still disclosed is a pharmaceutical composition that includes the present DHLA coated gold nanocluster. The pharmaceutical composition is useful for treating the inflammatory disease in the subject.

Method for treating inflammatory diseases

Disclosed herein is the novel use of a gold nanocluser for ameliorating oxidative stress and/or aging of a cultured cell or a subject having an oxidative stress and/or aging condition mediated by a vascular factor. The gold nanocluster has a particle size ranging from about 0.1 to 20 nm, and preferably is dihydrolipoic acid (DHLA) coated gold nanocluster.

Use of gold nanoclusters in ameliorating oxidate stress and/or aging

Growing community of inventors

Taipei, Taiwan

Hsueh-Hsiao Wang