Chang Gung University

Chang Gung Memorial Hospital, Linkou

Delta Electronics, Inc.

Hsin-Yao Wang

Min-Hsien Wu

Chih-Cheng Tsou

Chien-Ru Lin

Jang-Jih Lu

Chun-Hsien Chen

Chih-Kuang Chen

Wen-Pin Chou

Yi-Chen Li

Ting-Wei Lin

Yi-Yuan Chiu

Tzong-Shi Chiueh

Yi-Ju Tseng

Wan-Ying Lin

Tsui-Ping Liu

Song-Bin Huang

A method and a kit for detectingare provided. The method includes a step of performing a nested qPCR assay to a specimen. The nested qPCR assay includes a first round of amplification using external primers and a second round of amplification using internal primers and a probe. The external primers have sequences of SEQ ID NOs. 1 and 2, and the internal primers and the probe have sequences of SEQ ID NOs. 3 to 5.

Method and kit for detecting

An apparatus and method for examining an organism surface includes a pliable member including a contact layer, a plurality of channels, and a reaction layer, wherein the plurality of channels are disposed between the contact layer and the reaction layer; each of the channels having a size in the range of micrometers and formed of biocompatibility materials, and the contact layer including a plurality of spherical projections having a size in the range of micrometers and formed of biocompatible materials, and the reaction layer including examining molecules and a reaction unit.

Apparatus of examining surface of an organism and method thereof

An immunoassay includes forming first mixtures by reacting a combination reagent with serum of a subject; simultaneously forming second mixtures by reacting randomly selected platelet samples with the serum wherein in each mixture there are immunity compounds formed by combining the platelet antigens with predetermined antibodies in the serum, and other platelet antigens and other antibodies in the serum not forming the immunity compounds; preparing an interception device including receptacles and a filter net; placing each mixture in one receptacle; washing the mixtures wherein the mixtures forming the immunity compounds are intercepted by the filter net with others passing through; adding a signal sensing reagent to each receptacle; reacting the signal sensing reagent with the intercepted mixtures forming the immunity compounds to form final products; and performing a signal sensing to determine whether the final products contain anti-platelet antibodies and determine compatibility of cross matching of respective platelet samples.

Immunoassay for simultaneously screening anti-platelet antibodies and performing platelets cross matching and test apparatus for carrying out same

A method and a kit for detecting mycobacterium are provided. The method includes steps of: providing a sample; providing a pair of primers, which is selected from a group consisting of a sequence having about 45% to 100% similar to SEQ ID NO. 1, a sequence having about 60% to 100% similar to SEQ ID NO. 2, a sequence complementary thereof; performing a polymerase chain reaction by using the set of primers and the sample to obtain a product; and analyzing the product to detect the presence of the mycobacterium.

Method for detecting presence or absence ofand kit thereof

A method for establishing a computer-aided data interpretation model for immune diseases by immunomarkers and visualization is revealed. First combine a plurality of immunomarkers into an immunomarker panel. Then collect test data of a plurality of subjects measured by the immunomarker panel, and disease diagnosis information of the subjects for establishment of an immunomarker-panel testing database. Next new subjects are tested by the immunomarker panel. The data obtained and the corresponding information in the immunomarker-panel testing database are processed by unsupervised machine learning algorithm to get a computer-aided data interpretation model showing comparison of case distribution patterns. The method provides real-time analysis of multiple data to medical professionals for their reference. Thereby the correctness, the timeliness and the reproducibility of the interpretation result for the diagnosis and treatment of immune diseases are all improved.

Method for establishing computer-aided data interpretation model for immune diseases by immunomarkers and visualization

A method of creating characteristic peak profiles of mass spectra and identification model for analyzing and identifying microorganisms are provided. MALDI-TOF MS data of microorganisms having the same feature are gathered. Discretization of the data is performed. Density-based clustering is used to find m/z values of spectral peaks with high probability of occurrence from the discretized data. A characteristic MS peak profile is created for every specific feature of microorganisms. Every such a characteristic profile forms a feature template. The mass spectrum of each known isolate is matched against all the feature templates and a number of matched vectors are obtained. The matched vectors are then concatenated into a single 'integrated vector.' Then, a machine learning method and the integrated vectors generated from all known isolates are used to create a classification model for microorganism identification.

Method of creating characteristic peak profiles of mass spectra and identification model for analyzing and identifying microorganizm

An integrated bioinformatics sensing apparatus includes a piezoelectric sensing layer, an upper conductive layer, a bottom conductive layer and an information transmission controller. The piezoelectric sensing layer senses a physiological rhythm of a living organism to output a physiological rhythm signal, and the upper and bottom conductive layers sense a physiological electrical signal on a body surface of the living organism. The information transmission controller receives and processes the physiological rhythm signal and the physiological electrical signal to generate and store the sensed bioinformatics, or transmit the signals to the external processing device to display the sensed bioinformatics. The simple-structured sensing apparatus can be attached onto the body surface of the living organism conveniently.

Growing community of inventors

Chiayi, Taiwan

Hsin-Yao Wang