Duke University

Hsin-Neng Wang

Tuan Vo-Dinh

Andrew Fales

Tuan Vo-dinh

Tushar Krishnan

A diagnostic mobile health system for detecting biomarkers comprises an electronic device including an image sensor configured to capture image data, a sample housing configured to removably attach to the electronic device, and a computing device including at least one processor. The sample housing includes a slot to receive a sample container. The sample container received in the slot is positioned to allow the image sensor to capture image data for the sample when the sample housing is attached to the electronic device. The processor is configured for receiving, from the electronic device, image data for the sample that is captured by the image sensor of the electronic device when the sample container containing the sample is received by the sample housing attached to the electronic device and detecting at least one biomarker for the sample based on the received image data.

Smart phone platforms for mobile health

Plasmonics-active nanoprobes are provided for detection of target biomolecules including nucleic acids, proteins, and small molecules. The nucleic acids that can be detected include RNA, DNA, mRNA, microRNA, and small nucleotide polymorphisms (SNPs). The nanoproprobes can be used in vito in sensitive detection methods for diagnosis of diseases and disorders including cancer. Multiplexing can be performed using the nanoprobes such that multiple targets can be detected simultaneously in a single sample. The methods of use of the nanoprobes include detection by a visible color change. The nanoprobes can be used in vivo for treatment of undesireable cells in a subject.

Nano-plasmonic molecular probes and methods of use

Plasmonics-active nanoprobes are provided for detection of target biomolecules including nucleic acids, proteins, and small molecules. The nucleic acids that can be detected include RNA, DNA, mRNA, microRNA, and small nucleotide polymorphisms (SNPs). The nanoproprobes can be used in vito in sensitive detection methods for diagnosis of diseases and disorders including cancer. Multiplexing can be performed using the nanoprobes such that multiple targets can be detected simultaneously in a single sample. The methods of use of the nanoprobes include detection by a visible color change. The nanoprobes can be used in vivo for treatment of undesirable cells in a subject.

Growing community of inventors

Durham, NC, United States of America

Hsin-Neng Wang