Proview-mbd Biotech Co., Ltd.

Hsieh-Chih Tsai

Ging-Ho Hsiue

Wen-Yen Huang

Yu-Chia Chang

Shuian-Yin Lin

Yunn-Kuen Chang

Tzu-Yu Lin

Nai-Sheng Hsu

Synthetic amino acid-modified polymers and methods of making the same and using the same are disclosed. The synthetic amino acid-modified polymers possess distinct thermosensitive, improved water-erosion resistant, and enhanced mechanical properties, and are suitable of reducing or preventing formation of postoperative tissue adhesions. Additionally, the amino acid-modified polymers can also be used as a vector to deliver pharmaceutically active agents.

Amino acid-modified polymer for adhesion prevention and application thereof

The present invention relates to a composition comprising an amino acid-modified polymer, a carboxypolysaccharide, and may further include a metal ion for anti-adhesion and vector application. More specifically, the invention relates to a thermosensitive composition having enhanced mechanical and improved water-erosion resistant properties for efficiently preventing tissue adhesions and can serve as a vector with bio-compatible, bio-degradable/absorbable, and in-vivo sustainable properties.

Temperature sensitive composition for tissue adhesion prevention and application thereof

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Taipei, Taiwan

Hsieh-Chih Tsai