Bio-rad Laboratories, Inc.

Howard Willner

Vito J Mangiardi

Robert J Kapteyn

A reagent composition useful in assays for high density lipoprotein (HDL) cholesterol comprises heparin and a salt of a divalent metal cation such as MnCl.sub.2 dispersed in an inert filler comprising a polysaccharide, a terminal interlocking linear glucose polymer and a vinylpyrrolidone. The cholesterol containing serum sample acts as the milieu of the reaction as well as the solvent for the reagent composition itself.

High density lipoprotein cholesterol assay

Method for competitive binding in diagnostic clinical testing for thyroid function in which blood serum is sufficiently acidified to inactivate binding of thyroid hormone to serum proteins. The serum test solution is then mixed directly with a buffered competitive binding protein solution without first separating inactivated endogenous serum proteins.

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San Anselmo, CA, United States of America

Howard Willner