United States of America, As Represented by the Secretary of Agriculture

Howard V Davies

William R Belknap

Kent F McCue

David R Rockhold

Paul V Allen

Mary M Maccree

Louise V T Shepherd

Nucleic acid sequences from potato that encode the enzyme &#x3b2;-solanine/&#x3b2;-chaconine rhamnosyltransferase (SGT3) are disclosed. Recombinant DNA molecules containing the sequences, and use thereof, in particular, use of the sequences and antisense constructs to inhibit the production of SGT3 and thereby reduce levels of the predominant steroidal glycoalkaloids &#x3b1;-chaconine and &#x3b1;-solanine in Solanaceous plants such as potato are described.

[object Object]

Nucleic acid sequences from potato that encode the enzyme UDP-glucose:solanidine glucosyltransferase (SGT2) are disclosed. Recombinant DNA molecules containing the sequences, and use thereof, in particular, use of the sequences and antisense constructs to inhibit the production of SGT2 and thereby reduce the level of the more human-toxic of the two predominant steroidal glycoalkaloids &#x3b1;-chaconine and/or increase the level of the more insect-toxic &#x3b1;-solanine in Solanaceous plants such as potato are described.

Growing community of inventors

Invergowrie, United Kingdom

Howard V Davies