Bayer Aktiengesellschaft

Bayer Aktiengelsellschaft

Howard-Paul Rounding

Martin Bechem

Siegbert Hebisch

Alexander Straub

Rainer Gross

Siegfried Goldmann

Jurgen Stoltefuss

Joachim Hutter

Horst Boshagen

J Urgen Stoltefuss

Joachim H Utter

Klaus Dembowsky

Matthias Schramm

Gerhard Franckowiak

Joachim Hu/ Tter

Ju/ Rgen Stoltefuss

Ranier Gross

Siegfried Goldman

The invention relates to new 4-bicyclically substituted dihydropyridines of the general formula (I) ##STR1## in which R.sub.1 to R.sub.5 have the meaning given in the description, processes for their preparation and their use in medicaments, in particular in agents for the treatment of cardiovascular diseases.

4-bicyclically substituted dihydropyridines, and their use in medicaments

This invention relates to 3-quinolyl-substituted dihydropyridine derivatives, such as ##STR1## or a pharmaceutically acceptable salt thereof. These compounds are used in treating cardiovascular disease.

3-quinolyl-substituted dihydropyridines, and their use in medicaments

Intermediate of the formula ##STR1## wherein R.sup.5 represents a cyclic, straight-chain or branched, saturated or unsaturated hydrocarbon radical having up to 12 carbon atoms, which is optionally interrupted up to twice in an identical or different manner by oxygen or sulphur, as intermediates for substituents on novel dihydropyridine cardiovascular compounds.

3-quinolyl-substituted dihydropyridines, processes for their preparation

4-bicyclically substituted dihydropyridines and their use in medicaments

The invention relates to new 2,6-disubstituted 4-quinolyl-dihydropyridines ##STR1## in which R.sub.1 to R.sub.5 have the meaning indicated in the description, processes for their preparation and their use in medicaments, in particular in compositions for the treatment of cardiovascular disorders.

2,6-disubstituted 4-quinolyl-dihydropyridines

The invention relates to new 4-quinolyl-dihydropyridine esters of the general formula (I) ##STR1## in which R.sub.1 to R.sub.6 have the meaning given in the description, to processes for their preparation and to their use in medicaments, especially in agents for the treatment of cardiac circulatory disorders.

Quinolyl-dihydropyridine esters, processes for their preparation, and

The present invention relates to new 2-amino-5-cyano-4-quinolyl-l, 4-dihydropyridine esters of the general formula (I) ##STR1## in which R.sub.1 to R.sub.3 have the meaning given in the description, to processes for their preparation and to their use in medicaments, especially in agents for the treatment of cardiac circulatory disorders.

2-amino-5-cyano-4-quinolydihydropyridine esters, processes for their

The invention relates to new 3-quinolyl-substituted dihydropyridines, processes for their preparation and their use in medicaments, in particular in agents for the treatment of cardiovascular diseases.

3-quinolyl-substituted dihydropyridines and their use in medicaments

The present invention relates to new 2-amino-4-quinolyl-1,4-dihydropyridines of the general formula (I) ##STR1## in which R.sub.1 -R.sub.4 have the meaning given in the description, to processes for their preparation and to their use in medicaments, especially in agents for the treatment of cardiac circulatory disorders.

2-amino-4-quinolyl-dihydropyridines, processes for their preparation,

The present invention relates to new 2-amino-4-heteroaryl-1,4-dihydropyridines of the general formula (I) ##STR1## in which R.sub.1 to R.sub.4 have the meaning given in the description, processes for their preparation and their use in medicaments, in particular in compositions for the treatment of cardiovascular disorders.

Certain cinnoline carboxaldehydes and naphthyridine carboxaldehydes

The invention relates to novel, condensed 4-quinolyl-dhydropyridines of the general formula (I) ##STR1## in which A, R.sub.1, R.sub.2 and R.sub.3 have the meaning given in the description, to processes for their preparation and to their use in medicaments, in particular in agents for treating angiocardiopathies.

Condensed quinolyl-dihydropyridines, processes for their preparation and

The present invention relates to new 2-amino-4-hetero-aryl-1,4-dihydropyridines of the general formula (I) ##STR1## in which R.sub.1 to R.sub.4 have the meaning given in the description, processes for their preparation and their use in medicaments, in particular in compositions for the treatment of cardiovascular disorders.

2-amino-4-heteroaryl-1,4-dihydropyridines and their use in medicaments

The present invention relates to new 2-amino-5-cyano-4-quinoline-1,4-dihydropyridines, processes for their preparation and their use in medicaments, in particular in agents for the treatment of cardiovascular diseases.

Process for preparing 1,4-dihydro-2-amino-3-carboxy-5-cyano-pyridine

The present invention relates to the use of 3-formyl-1,4-dihydropyridine derivatives as medicaments for the control of cardiovascular diseases, in particular of pathologically changed blood pressure and of cardiac insufficiency, new compounds and a process for their preparation.

Certain 3-formyl-1, 4-dihydropyridines and their pharmaceutical

The invention relates to new 4-cinnolinyl- and 4-naphthyridinyl-dihydropyridines of the general formula I ##STR1## in which R.sup.1 to R.sup.5 have the meaning given in the description, to processes for their preparation and intermediates thereof and to their use in medicaments, in particular in compositions having positively inotropic action.

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Wuppertal, Germany

Howard-Paul Rounding