Other

Clinical Technologies Associates, Inc.

Howard M Pack

Solomon S Steiner

Martin L Kantor

Microcapsules containing oil-based biologically active compounds which are stable over extended time periods for release of the encapsulated compound in the intestine. There are a number of biologically active compounds having an oil base which must be orally ingested in order to have a beneficial effect. An example of one such biologically active oil-based compound is a fish oil having a high content of polyunsaturated omega-3 fatty acids which has been demonstrated to reduce plasma levels of triglycerides, very low density lipoprotein, low density lipoproteins and cholesterol in normal and hyperlipidemic subjects. The disclosed microcapsules eliminate the unfortunate problems of the unpleasant taste and smell of the fish oil, as well as the aftertaste, particularly when ingested in large quantities, and provide a palatable and practical means of ingesting efficacious quantities of fish oil. In addition, the normal oxidation of polyunsaturated fatty acids is inhibited.

Microencapsulation of fish oil

A method for reducing weight by the administration of L-Dopa or a stabilized form thereof with or without a decarboxylase inhibitor and Molindone wherein Molindone acts as a potentiator to enhance the weight reducing potency of L-Dopa in warm-blooded animals. The synergistic effect of the combination of L-Dopa and Molindone reduces the required dosage of the two drugs to levels which can be tolerated by higher forms of mammals, whereas individually the dosages required to reduce weight in higher mammals is not easily tolerated and may be toxic or lead to undesirable side effects.

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Scarsdale, NY, United States of America

Howard M Pack