University Technologies International, Inc.

Pan-Eco S.a.

Howard Ceri

Merle Edwin Olson

Douglas Walter Morck

Andre Gerald Buret

Ronald Rae Read

Raymond Joseph Turner

Fabrizio Rivardo

Maria Giovanna Martinotti

Gianna Allegrone

Newstrain named V9T14 that produces a new biosurfactant composition that is effective against colonization and/or bio film formation from bacteria. The new biosurfactant composition can be used in combination with biocides for preventing formation and/or for eradicating bacteria grown planktonically and/or as a biofilm, preferably on biotic and/or abiotic surfaces.

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Biofilm forming organisms are incubated to form a biofilm on projections by providing a flow of liquid growth medium across projections, the direction of the flow of liquid being repeatedly changed, and an assay made of the resulting biofilm. Biofilm forming organisms are incubated to form a biofilm on projections arranged in rows, with several projections in each row, while providing a flow of liquid growth medium across each row of projections, and an assay made of the resulting biofilm. Sensitivity of the biofilm to antimicrobial reagent may be determined by treating the projections with antimicrobial reagent before carrying out the assay, by treating each row of projections with a different antimicrobial reagent, and each of the projections in a row with a different concentration of antimicrobial reagent.

Method of assaying the susceptibility of biofilms to anti-microbial agents

A method for testing the performance of surface coatings on the formation of biofilm and encrustation on materials. The method includes, providing a plurality of material retaining sites, providing the material retaining sites with a material, wherein the material models a surface likely to be involved in biofilm formation and encrustation deposit. The method further includes the steps of providing a liquid growth medium, wherein the liquid growth medium includes at least one microorganism, the liquid growth medium arranged to cover at least a portion of the material, and incubating microorganism and encrustation on the material retaining sites in the presence of the liquid growth medium.

Effects of materials and surface coatings on encrustation and biofilm formation

Bacteria are incubated to form a biofilm on projections by providing a flow of liquid growth medium across projections, the direction of the flow of liquid being repeatedly changed, and an assay made of the resulting biofilm. Bacteria are incubated to form a biofilm on projections arranged in rows, with several projections in each row, while providing a flow of liquid growth medium across each row of projections, and an assay made of the resulting biofilm. Sensitivity of the biofilm to antibacterial reagent may be determined by treating the projections with antibacterial reagent before carrying out the assay, by treating each row of projections with a different antibacterial reagent, and each of the projections in a row with a different concentration of antibacterial reagent.

Method of growing and analyzing a biofilm

The present invention relates to an apparatus and methods for testing the formation of biofilms on various materials. The apparatus includes a lid and a vessel, wherein the lid may be configured to accept various materials for the testing of biofilm formation. For example, the lid may contain a plurality of projections onto which materials may be coated or disposed. The vessel is adapted to receive the lid in a fluid tight communication and to retain a liquid growth medium therein. After a material has been disposed upon the projections, the material is suspended within the vessel containing the liquid growth medium. The material is allowed to incubate for a period of time in which a biofilm forms upon the material. The material is then removed from the liquid growth medium and the biofilms formed thereupon are used to test the efficiency of various biocides.

Apparatus and methods for testing effects of materials and surface coatings on the formation of biofilms

Method of making biofilms

Bacteria are incubated to form a biofilm on projections by providing a flow of liquid growth medium across projections, the direction of the flow of liquid being repeatedly changed, and an assay made of the resulting biofilm. Bacteria are incubated to form a biofilm on projections arranged in rows, with several projections in each row, while providing a flow of liquid growth medium across each row of projections, and an assay made of the resulting biofilm. Sensitivity of the biofilm to antibacterial reagent may be determined by treating the projections with antibacterial reagent before carrying out the assay, by treating each row of projections with a different antibacterial reagent, and each of the projections in a row with a different concentration of antibacterial reagent. A biofilm assay device includes a vessel including at least one channel for flow of liquid growth medium, projections arranged in at least one row and having a support for supporting the projections within the channel, and a tilt table to flow liquid growth medium along each channel in different directions across the projections. A further biofilm assay device includes a vessel including channels for flow of liquid growth medium, projections arranged in rows and having a support for supporting the projections within the channels, and a rocking table to rock the vessel and flow liquid growth medium along each channel across the projections.

Biofilm assay

The invention provides vaccines and methods for preventing or treating intestinal protozoal infections in an animal. In particular, vaccines and methods for prevention or treatment of giardiasis are provided. The invention also encompasses methods of preparing and methods of use of novel toxins, antibodies, vaccine strains and compositions that result from or are used in these methods.

Intestinal protozoal vaccines

Giardia treatment and antibody

Vaccines and methods for preventing or treating intestinal protozoal infections in an animal. In particular, vaccines and methods for prevention or treatment of giardiasis are provided. The invention also encompasses methods of preparing and methods of use of novel toxins, antibodies, vaccine strains and compositions that result from or are used in these methods.

Growing community of inventors

Calgary, Canada

Howard Ceri