Genelex Corporation

Other

Invitae Corporation

Youscript Inc.

Youscript Technologies LLC

Howard C Coleman

Robert D Patterson

Jessica Oesterheld

Kristine Ashcraft

Rajeev V Pany

Example methods of quantifying known and unknown risks of an adverse drug event in an individual based on various factors are disclosed. In some embodiments, factors include known drug-drug interactions and unknown phenotypes of cytochromes. Quantification may be based on severity of the adverse drug event/and or probability of occurrence in some embodiments. Example methods of displaying the quantified risk are also disclosed. In one embodiment, the risk of individuals is aggregated to display the risk of a population.

Systems and methods for quantification and presentation of medical risk arising from unknown factors

A computerized tool and method for delivery of pharmacogenetic and pharmacological information, comprising a core system having algorithms and databases for storing, collating, accessing, cross-referencing, and interpreting genetic and pharmacologic data, with a graphical user interface for a client network of providers of laboratory genetic testing services to access the core services under contract. The system includes 'paypoints' in support of improved business models. Included are mechanisms for 'pass through' third party and insurance reimbursement for interpretive reports, insurance reimbursement for on-line access to pharmacogenetic information at the point of care, tools for market segmentation, and a conversion tool for capturing new subscribers. Also disclosed are tools and predictive algorithms for preventing drug-drug and drug-gene adverse drug reactions.

Genetic data analysis and database tools

A fluid circulation apparatus for an electrophoresis device is disclosed. The fluid circulation device has an electrode gas retaining means communicating with the two reservoirs of the electrophoresis device. The electrode gas retaining means is disposed to trap electrode produced gas at a level below the fluid level in the remainder of the electrophoresis device so that fluid in the electrode gas retaining means has a pressure head greater than the pressure at the fluid level in the remainder of the electrophoresis device. The resulting fluid pressure differential causes the fluid flow between the two reservoirs of the electrophoresis device through the electrode gas retaining means.

Electrophoresis buffer circulation apparatus

A rotary internal combustion engine is shown having a combination of reaction nozzle means and turbine elements to extract energy from a stream of hot gases. A centrifugal air compressor feeds a rotary diffusion combustion chamber to operate the reaction nozzles. The products of combustion issuing from the nozzles are redirected by stationary vanes to drive a turbine to extract further energy from the gas flow as it passes to the exhaust.

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Seattle, WA, United States of America

Howard C Coleman