Other

Nano Hesgarsazan Salamat Arya

Hossein Simaee

Mohammad Abdolahad

Mohammad Ali Khayamian

Mahsa Faramarzpour Darzini

Hamed Abadijoo

Shahriar Shalileh

Mohammad Reza Ghaderinia

Shohreh Vanaei

Mohammad Salemizadeh Parizi

Seyed Mojtaba Yazdanparast

Mohammadreza Ghaderinia

A method for preventing cytokine storm by suppressing clonal expansion of hyperactivated lymphocytes in a COVID-19 infected patient. The method includes placing at least four electrodes on skin of the COVID-19 infected patient by putting at least two electrodes at two locations over chest in front of ribcage of the COVID-19 infected patient and putting at least two other electrodes at two locations adjacent to lung tissue of the COVID-19 infected patient and suppressing mitosis of hyperactivated proliferative lymphocytes cells within the lung tissue of the COVID-19 infected patient by electrically stimulating the hyperactivated proliferative lymphocytes. Electrically stimulating the hyperactivated proliferative lymphocytes includes generating an alternating electric field (AEF) within the lung tissue by applying an AC voltage to the at least four electrodes and periodically changing a direction of the generated AEF in a plurality of directions within the lung tissue.

Preventing cytokine storm in COVID-19 patients by suppressing clonal expansion in activated lymphocytes using alternating electric fields

A method for diagnosing COVID-19 infection. The method includes drawing a blood sample from a person suspected to be infected with COVID-19 virus, separating a blood serum sample from the blood sample by centrifuging the blood sample, recording an electrochemical impedance spectroscopy (EIS) associated with the blood serum sample, calculating a charge transfer resistance (R) of the recorded EIS by measuring a diameter of a semicircular curved part of the recorded EIS, and detecting a COVID-19 infection of the person based on the calculated Rif the calculated Ris equal to or more than a threshold value.

Real-time tracing of cytokine storm in blood serum of COVID-19 patients

A system for diagnosing COVID-19 infection. The system includes a biosensor, an electrochemical stimulator-analyzer, and a processing unit. The biosensor is configured to be put in contact with a blood serum sample of a person suspected to be infected of COVID-19 virus. The processing unit is configured to apply an AC potential amplitude to the biosensor while sweeping a frequency range utilizing the electrochemical stimulator-analyzer, recording an electrochemical impedance spectroscopy (EIS) associated with the blood serum sample utilizing the electrochemical stimulator-analyzer, calculating a charge transfer resistance (R) of the recorded EIS, and detecting a COVID-19 infection of the person based on the calculated Rif the calculated Ris equal to or more than a threshold value.

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Tehran, Iran

Hossein Simaee