The Governors of the University of Alberta

Hossein Salimi-Moosavi

Richard H Smith

D Jed Harrison

Daniel Jed Harrison

Gregor Ocvirk

Per Andersson

Paul C H Li

Roderick Szarka

Yutao Jiang

Nghia H Chiem

Graham H McKinnon

This invention relates to a novel microfluidic device and methods of using this device to conduct in vitro studies on the reaction and effects of various compounds on cells. More particularly, it relates to a method for using stop flow in a microfluidic system to study the effect of compounds on individual cells. It also provides a method for observing the effects of candidate compounds on leukocyte rolling.

Microfluidic system and methods of use

An improved absorbance or detection cell for a microfluid device, and in accordance with an aspect of the invention, the absorbance cell comprises a bottom plate having a channel bearing surface in which a channel having a fluid inlet and fluid outlet is defined, a top plate having a channel facing surface bound to the channel bearing surface of the bottom plate and first and second reflecting elements formed on opposed sides of the channel to form a waveguide through which the channel extends such that radiation propagating along the waveguide makes multiple passes across the channel, the waveguide having a radiation input end and a radiation output end.

Absorbance cell for microfluid devices

Growing community of inventors

Edmonton, Canada

Hossein Salimi-Moosavi