Irvine Biomedical, Inc.

Other

Glaukos Corporation

Quantum Therapeutics Corp.

3F Therapeutics, Inc.

Quantumcor, Inc

Polymerex Medical Corp.

Hosheng Tu

Weng-Kwen Raymond Chia

Lily Chen Tu

Cary K Hata

Alan De La Rama

Rodolfo C Quijano

Morteza Gharib

Steve Chun-Guang Tu

Olav B Bergheim

Chi-Wu James Chang

Tho Hoang Nguyen

Daniel H Duff

Yu-An Chang

Olav G Bergheim

Cheng-Liang Lu

A trabecular shunt and methods for treating glaucoma are disclosed. One of the methods comprises transporting fluid from the anterior chamber of an eye to Schlemm's canal through an implant, the implant extending between the anterior chamber and Schlemm's canal; sensing an intraocular pressure using a sensor incorporated into the implant; and transmitting a signal indicative of the sensed pressure to an external receiver.

Implant with pressure sensor for glaucoma treatment

This invention discloses a medical catheter and methods for removing a defective valve from a patient endoluminally. The method may comprise inserting a medical catheter endoluminally to a site of the defective valve; deploying a coupling mechanism of said medical catheter to stabilize and immobilize a free edge of at least one valve leaflet; deploying a cutting mechanism of said medical catheter to cut a valve base of said defective valve; and removing said defective valve from the patient.

Apparatus and methods for valve removal

A glaucoma treatment device for directing the flow of aqueous humor and bypassing trabecular meshwork is disclosed. The device comprises an inlet section, an outlet section, a middle section, and at least one lumen for transmitting aqueous humor within the glaucoma device. The lumen extends through at least one of the sections, and the outlet section is substantially perpendicular to the middle section, and fits within a conduit of aqueous humor outflow in the eye.

Glaucoma treatment device

The current invention discloses a catheter and a method for delivering a stentless bioprosthesis in a body channel, the method comprising percutaneously introducing a catheter into the body channel, wherein the catheter contains said stentless bioprosthesis at a retracted state; and disengaging said stentless bioprosthesis out of a distal opening of the catheter by a pulling mechanism associated with the catheter structure.

Delivery system for a stentless valve bioprosthesis

A trabecular shunt and methods for treating glaucoma are disclosed. The method comprises placing a trabecular shunt through diseased trabecular meshwork, between the anterior chamber and Schlemm's canal. The trabecular shunt includes a hollow, elongated tubular element having an inlet section and an outlet section. The outlet section includes two bifurcatable elements adapted to be positioned and stabilized inside Schlemm's canal.

Bifurcatable trabecular shunt for glaucoma treatment

A vascular graft comprising Vascular Endothelial Growth Factor (VEGF) and/or Platelet Derived Growth Factor (PDGF) for enhanced site-specific angiogenesis and methods thereof are disclosed. At least one VEGF, PDGF or angiogenesis factor is incorporated into the vascular graft to facilitate enhanced angiogenesis so as the cells are stimulated to migrate to environments having higher concentration of growth factors and start mitosis.

Device for treating diabetes and methods thereof

An ablation device system for treating tissues in a patient, the ablation device comprising capabilities for temperature sensing and providing ablation energy hyperthermically or hypothermically for treating tissue.

Medical device having temperature sensing and ablation capabilities

An apparatus and methods for enhanced plasmapheresis comprising a filter membrane under an orbital motion or movement that has optimal local shear forces and maximum plasma flow output. The separation apparatus comprises a first plate, a second plate and a hollow interior therebetween, wherein the second plate is detachably coupled to a non-rotational drive structure that controls the second plate in an orbital motion in reference to a center axis of the first plate for enhanced blood separation.

Method and apparatus for enhanced plasmapheresis

An expandable annuloplasty ring which may be enlarged in situ comprising essentially uniform ring distension in the circumferential direction. The expandable annuloplasty ring is usable in pediatric patients whose growth necessitates enlargement of the ring by application of shape-memory material by way of heat activation or other non-mechanical means to accommodate growth of the annulus. The invention includes a non-contact method for post-implantation enlargement of the annuloplasty ring via a magnetic circuit or an external heat source.

Expandable annuloplasty ring and methods of use

A medical device for treating the hemorrhoid, or reducing the dilatation of cellular tissues comprising ligating a hemorrhoid tissue and heating the hemorrhoid tissue. In one embodiment, an elongate tubular shaft comprises at least one coil loop electrode arrangement disposed at the distal end portion of the shaft, a RF energy generating source, and a method for deploying a dilated ligature element to effect the pressure therapy for the hemorrhoid tissues.

Device for treating tissue and methods thereof

A medical device for treating gingivae or reducing the mass of cellular tissue, wherein an elongated tubular element comprises at least one electrode disposed of at its distal section, the energy generating means, and means for generating vibration at the distal section of the tubular element to effect the heat treatment and the vibrational massage therapy for the targeted tissue.

Medical device and methods thereof

A medical device for treating intravascular restenosis of a patient, the medical device comprising a catheter shaft and an inner catheter, the inner catheter having a deployable wire assembly arrangement, wherein the deployable wire assembly arrangement comprises a plurality of preshaped expandable metallic basket members at the distal end of the inner catheter adapted to contact a pre-implanted stent and to apply RF current to the tissues for therapeutic purposes through a wire guide shaft. Alternately, a plurality of expandable metallic basket members are secured to the distal section of the catheter shaft for contacting a pre-implanted stent of the patient through a wire guide shaft.

Medical device and methods for treating intravascular restenosis

An ablation catheter system and methods for repairing an annular organ structure comprising high frequency ablation for the purposes of tightening and stabilizing a tissue. A catheter suitable for high frequency ablation comprises a flexible tissue-contactor means located at the distal tip section of a catheter shaft for contacting an inner wall of the annular organ structure, and a needle electrode means located at or within the flexible tissue-contactor means for penetrating into the tissue, wherein the needle electrode means is deployable out of the tissue-contactor means in a manner essentially perpendicular to a longitudinal axis of the catheter shaft.

Ablation catheter system and methods for repairing a valvular annulus

A catheter-based method for coronary sinus mapping, pacing, and ablation, wherein a distal tip portion having longitudinally stretchable/compressible capability is pre-shaped to snugly fit into the coronary sinus with resilience and trauma-free manner, so that the distal tip portion is positioned in the sinus; the distal tip portion is deflected to expose a plurality of electrodes; and RF energy is then applied to the coronary sinus tissue through the electrodes to cause pacing, mapping, and/or ablation.

Devices and methods for coronary sinus mapping

An improved guiding catheter system having inflated balloon at its tip section, wherein the inflated balloon having a plurality of electrodes is heated to a predetermined temperature as an ablation means for delivering the thermal energy to a tissue by deploying the balloon to contact the tissue to cause a circular ablation lesion, the plurality of electrodes using RE energy as a heat source for paroxysmal atrial fibrillation indications.

Growing community of inventors

Tustin, CA, United States of America

Hosheng Tu