Symrise Ag

Haarmann & Reimer Gmbh

Symrise Gmbh & Co Kg

Basf Se Corporation

Horst Surburg

Arnold Machinek

Hubert Loges

Heiko Oertling

Ulrike Simchen

Erich Dilk

Stefan Lambrecht

Horst Sommer

Wolfgang Siegel

Thomas Subkowski

Michael Backes

Oskar Koch

Claus Bollschweiler

Roland Langner

Jens Wittenberg

Steffen Sonnenberg

Peter Worner

Volkmar Koppe

Ralf Pelzer

Rudolf Hopp

Gerhard Krammer

Bernd Hölscher

Günter Kindel

Matthias Guntert

Matthias G&uuml;ntert

Walter Kuhn

Leslie C Smith

Heinz-Jurgen Bertram

Georg Ronge

Stephan Klein

Tobias Vössing

Christine Mendoza-Frohn

Keith J McDermott

Johannes Panten

Marcus Eh

Jan Looft

Kai Verkerk

Alfred Krempel

Peter W&ouml;rner

Stephan Hillers

Aurelia Reckziegel

Ute Rohde

Dirk M&uuml;ller

Peter Esser

Thomas Obrocki

Karl Sparkuhle

G&uuml;nter Kindel

Klaus Sorge

Arturetto Landi

Gerhard Scheideler

The invention relates to a TRPM8 modulator for achieving a cooling effect on the skin or a mucous membrane.

Use of physiological cooling active ingredients, and agents containing such active ingredients

The present invention primarily concerns teeth cleaning compounds containing menthol for use with a toothbrush, preferably tooth pastes, tooth cr&#xe8;mes, tooth cleaning gels or tooth powders. Such a tooth cleaning compound according to the invention contains menthol and a quantity, for masking the bitterness of the menthol, of menthane carboxylic acid-N-(4-methoxyphenyl)-amide (WS-12) of the following formula (Ia), in particular of the following formula (Ib), i.e. L-menthane carboxylic acid-N-(4-methoxyphenyl)-amide.  The present invention also concerns the use of menthane carboxylic acid-N-(4-methoxyphenyl)-amide (WS-12) of the formulas (Ia) or (preferably) (Ib) to mask the bitter taste of menthol in a teeth cleaning compound. The present invention also concerns a method for dissolving menthane carboxylic acid-N-(4-methoxyphenyl)-amide (WS-12) in a teeth cleaning compound and a method for masking the bitterness of menthol in a teeth cleaning compound.

Products comprising a flavoring agent composition

A preparation for creating a clearing feeling in a pharyngeal cavity and nasal cavity comprising a rhinologically active substance of formula (I):  In formula (I), variable x and substituents R, Rand Rhave the following meanings:

Utilization of rhinologically active substances

The present invention relates to d,l-menthol and optionally additionally l-menthol-containing mixtures, which are liquid at normal pressure and a temperature of 20&#xb0; C. or higher. The present invention further relates to products that comprise such a mixture or that are preparable by mixing or contacting such a mixture with further ingredients, and novel processes for preparing menthol-containing products.

Mixture containing menthol

The present invention relates to specific oxalic acid derivatives and to corresponding mixtures and to uses thereof as physiological cooling active ingredients.

Oxalic acid derivatives and use thereof as physiological cooling active ingredients

The present invention relates to depot preparations for the targeted release of an aldehyde together with two carboxylic acids, where the released aldehydes are organoleptic substances, specifically fragrances or flavorings, and these depot preparations are prepared by reacting aldehydes with carboxylic anhydrides.

Depot preparations

The invention relates to a mixture of compounds having the sensory properties of wintergreen, to fragrance and flavoring compositions containing said mixture and to flavored and perfumed products containing said mixture, to a method of adding a wintergreen flavor, odor or note to (non-wintergreen) flavored or perfumed products. Further the present invention relates to the use of said mixture as an enhancement, or as complete or partial replacement for methyl salicylate, in particular in chewing gum, foods, dentrifices, mouthwashes and other orally consumable products. The mixture comprises or consists of dihydroanethole, o-anisaldehyde, 1,3-dimethoxybenzene, 2'-hydroxyacetophenone, and optionally 2-methoxyacetophenone.

Mixture with wintergreen odor and flavor

The present invention concerns mixtures with cis-3,3,5-trimethylcyclohexyl esters and trans-3,3,5-trimethylcyclohexyl esters, the use of cis-3,3,5-trimethylcyclohexyl esters as fragrance substances and individual cis-3,3,5-trimethylcyclohexyl esters and their uses.

Cis-3,3,5-trimethylcyclohexyl esters

Compounds of formula (A) are described wherein, independently of one another, the following applies to groups R and R:

2-alkoxymethyl-3-isoalkenyl-1-methylcyclopentenes, use thereof, in particular as fragrance substances, corresponding articles and production methods

The use of 4-isoamylcyclohexanol [4-(3-methylbutyl)-cyclohexan-1-ol], in particular of cis-4-isoamylcyclohexanol, as an odoriferous or aroma substance, in particular as a flowery odoriferous substance which is distinguished especially by rose and geranium notes, is primarily described. Certain mixtures of cis- and trans-4-isoamylcyclohexanol and a process for the preparation of these mixtures are additionally described.

4-isoamylcyclohexanol as odiferant

A mixture of 17-oxabicyclo[14.1.0]heptadec-8-ene and its isomers as an odoriferous substance and an odoriferous or aroma substance mixture comprising 17-oxabicyclo[14.1.0]heptadec-8-ene and one or more further odoriferous or aroma substances are described.

Mixtures of unsaturated macrocyclic epoxides as odoriferous substances

3-Methylbenzyl isobutyrate is described, as is the use thereof as an odoriferous substance, in particular for imparting a green fruity head note to an odoriferous substance mixture.

3-methylbenzyl-isobutyrate

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Holzminden, Germany

Horst Surburg