United Therapeutics Corporation

Siemens Aktiengesellschaft

Joanneum Research Forschungsgesellschaft Mbh

Cbmed Gmbh Center for Biomarker Research in Medicine

Lbi-lvr-ludwig Boltzmann Institute Lung Vascular Research of the Ludwig Boltzmann Gesellschaft Gmbh

Medizin Medizinische Universitat Graz

Horst Olschewski

Thomas Schmehl

Werner Seeger

Lewis J Rubin

Robert Voswinckel

Robert Roscigno

Carl Sterritt

Gabor Kovacs

Rainer Kurt Rienmueller

Christoph Magnes

Sophie Narath

Edgar Gander

Andrea Olschewski

Bence M Nagy

Gert Reiter

Natalie Bordag

Ursula Reiter

Treprostinil can be administered using a metered dose inhaler. Such administration provides a greater degree of autonomy to patients. Also disclosed are kits that include a metered dose inhaler containing a pharmaceutical formulation containing treprostinil.

Treprostinil administration by inhalation

The present invention relates to a method of diagnosing pulmonary hypertension (PH) in a patient, a method of monitoring the course of pulmonary hypertension in a patient, a method of determining the severity of pulmonary hypertension in a patient, and a method of differentiating between pulmonary hypertension and at least one condition selected from a group consisting of a disease associated with a risk of developing pulmonary hypertension and metabolic syndrome. In addition, the present invention relates to a kit comprising means for carrying out the above methods.

Biomarker for the diagnosis of pulmonary hypertension (PH)

In a method and apparatus for examination and evaluation of a blood flow in a pulmonary artery of a patient, measurement data are recorded, from which at least a part of the blood flow in the pulmonary artery is able to be re-constructed at least two-dimensionally in a plane defined by a longitudinal axis of the pulmonary artery and by an anterior-posterior direction, including at least at several diastolic points in time in the course of a heart cycle, after a closure of the pulmonary valve. The number of diastolic points for which an asymmetry in relation to the longitudinal axis of the pulmonary artery in the anterior-posterior direction exists is determined. A measure is then determined that characterizes how long, after the closure of the pulmonary valve, the aforementioned asymmetry exists.

Method and medical apparatus for measuring pulmonary artery blood flow

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Graz, Austria

Horst Olschewski