Schott Ag

Horst Koller

Matthias Bicker

Robert Hormes

Daniel Haines

Luis Burzio

Manfred Lohmeyer

Hartmut Bauch

Samuel David Conzone

Markus Steigenberger

Jasmina Marjanovic

Jasmina Buki

Karl Mosimann

Thomas Kadur

Joachim Pfeifer

Daniel Edward Haines

The present invention relates to a multi-functional pharmaceutical package surface and a method of preparing a multi-functional pharmaceutical package surface. In particular, the present invention relates to a pharmaceutical package having a protein deterrent and lubricious surface and methods of preparing said surface by applying coatings directly to the pharmaceutical package that (a) reduce the adsorption of proteins onto pharmaceutical packaging while not affecting the activity of the protein solution and (b) provide a lubricious surface. The pharmaceutical package surface may also contain a barrier coating. Coatings can be deposited on a variety of pharmaceutical packaging materials and configurations by various methods.

Pharmaceutical package having a multi-functional surface and a method of preparing a multi-functional surface on a pharmaceutical package

A method of preparing a macromolecule deterrent surface on a pharmaceutical package. In particular, the present invention relates to a method of preparing a protein deterrent surface on a pharmaceutical package by applying a coating or coatings directly to the pharmaceutical package that reduces the adsorption of proteins onto pharmaceutical packaging while not affecting the activity of the protein solution contained.

Method of preparing a macromolecule deterrent surface on a pharmaceutical package

The syringe is formed according to DIN ISO 11040 and has a syringe barrel () with a syringe head () formed on one end and a grip plate () formed at the other open end. An elastomeric piston stopper () is insertable in this open end, which is movable back and forth and which has a cruciform-cross-sectioned piston rod () screwed into it. A stop element, which reduces the interior diameter of the syringe barrel, is provided at the open end of the syringe barrel to perform a back-stop function, i.e. to prevent unintended withdrawal of the piston stopper. For this purpose a plastic part () connected to the grip plate () is provided with snap catches (), which snap onto the inner side of the syringe barrel (). These snap-catches () prevent the piston rod () from being rotated out of the piston stopper and the piston stopper () from being withdrawn from the syringe barrel. At the same time the finger support is enlarged.

Medicinal syringe with piston stopper withdrawal and rotation-limiting means

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Engelburg, Switzerland

Horst Koller