Meadox Medicals, Inc.

Scimed Life Systems, Inc.

Collagen Matrix, Inc.

Horng-Ban Lin

David J Lentz

Shu-Tung Li

Richard J Zdrahala

Debbie Yuen

Birendra K Patnaik

Nicholas Popadiuk

Disclosed are implantable medical devices with enhanced patency. Expanded polytetrafluoroethylene small caliber vascular grafts coated with polymer bound bio-active agents that exhibit enhanced patency are disclosed. The polymer bound bio-active agents can include anti-thrombogenic agents, antibiotics, antibacterial agents and antiviral agents. Methods of preparing same are also provided.

Method for imparting a bio-active coating

ePTFE small caliber vascular grafts with significant patency enhancement via a surface coating which contains covalently bonded heparin

A flexible implantable luminal device is disclosed, which is made from a porous cylindrical tube manufactured from extruded fluoropolymer. A fluoropolymer filament is wrapped helically around the external surface of the tube. The filament is fused to the tube to form a unitary composite structure by heating the wrapped tube to a temperature above the melting points of the fluoropolymers. The resulting composite is a radially reinforced flexible luminal prosthesis suitable for implantation, particularly, as a vascular graft or endoprosthesis. Also disclosed is a method for manufacturing the prosthesis.

PTFE implantable tubular prostheses with external coil support

Growing community of inventors

Randolph, NJ, United States of America

Horng-Ban Lin