Boston Scientific Scimed, Inc.

Collagen Matrix, Inc.

Boston Scientific Corporation

Boston Scientific Limited, an Irish Company

Horng-Ban Lin

Huisun Wang

Jeffrey S Lindquist

Richard Charles Gunderson

Peter G Edelman

Scott Fisher

Pu Zhou

Hancun Chen

Yem Chin

James M Anderson

Shu-Tung Li

Justin M Crank

Jeffrey H Vogel

Sheng-Ping Zhong

Debbie Yuen

James Q Feng

James G Hansen

Mark Steven Smith

Mel R Beulke

The Thomas Trinh Tran

Kinh-Luan D Dao

Steve Kangas

Gary R Kostur

Narin Anderson

David K Johnson

A prosthetic heart valve includes a base and a plurality of polymeric leaflets. Each leaflet has a root portion coupled to the base, and each leaflet has an edge portion substantially opposite the root portion and movable relative to the root portion to coapt with a respective edge portion of at least one of the other leaflets of the plurality of leaflets. Each leaflet includes) at least two polymers along at least one portion of the leaflet, and each leaflet has a composition gradient of each of the at least two polymers along at least one portion of the leaflet.

Prosthetic heart valve formation

Medical devices and methods for manufacturing and using medical devices. An example medical device includes a core member, a tubular member coupled to the core member, and a tip member coupled to the tubular member. The tubular member may have a plurality of slots formed therein. The tip member may include a polymeric material. An intermediate member may be disposed between the tubular member and the core member that aids the bonding of the tip member thereto.

Crossing guidewire

Medical devices and methods for making and using the same are disclosed. An example medical device may include a guidewire. The guidewire may include an elongate shaft. The shaft may include a porous metal alloy. The porous metal alloy may be arranged so that the porous metal alloy has a first pore distribution along a first portion of the shaft and a second pore distribution different from the first pore distribution along a second portion of the shaft.

Guidewires including a porous nickel-titanium alloy

An embolic protection filter having an improved filter frame and method of making the same. In at least some embodiments, the present invention includes an embolic protection filter coupled to an elongate shaft. The filter may include a filter frame assembly having one or more frame members. The frame members may include a filter mouth defining portion.

Embolic protection filter having an improved filter frame

An embolic protection filter and method of making the same. An embolic protection filter may include a filter membrane or material having a plurality of holes. In some embodiments, the filter membrane may be manufactured by spray coating a filter material onto a forming member or spray mold.

Filter membrane manufacturing method

This invention relates to an embolization device for occluding a vessel. This device includes a matrix made of a biocompatible and biopolymeric material and a radiopaque material, wherein the radiopaque material is interspersed in the biocompatible and biopolymeric material. The matrix can adopt a linear extended form or a folded relaxed form.

Embolization device

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Maple Grove, MN, United States of America

Horng-Ban Lin