Idexx Laboratories, Inc.

Idezz Laboratories, Inc.

Hongzhi Xie

Murthy V S N Yerramilli

Giosi Farace

Daniel Wayne Patch

Yingzi Wu

Evan M Peck

Jennifer E Gagner

Paul J Travers

James R Salter

Sreenivasa Rao Ramisetty

Murthy Vsn Yerramilli

Christopher P Turmel

Kiamars Hajizadeh

The present invention relates to a method and reagents for determining the presence of or the amount of an analyte in a sample.

Fluorescence quenching immunoassay

Homogeneous immunoassays that allow for compensation of background signals inherent in samples and reagents. The use of homogeneous immunoassays for the detection of the presence or amount of symmetrical Dimethyl Arginine (SDMA) in biological samples. Reagents and kits for conducting the assays.

Homogenous immunoassay with compensation for background signal

The disclosure generally relates to the detection of symmetrical dimethylarginine (SDMA). More particularly, the disclosure relates to the detection of SDMA using a solid phase. The disclosure provides devices, reagents, kits and methods for detecting symmetrical dimethyl arginine (SDMA) in sample, such as a biological sample from an animal. The method includes detecting the presence or amount of SDMA in the sample by using an immunoassay format, such as a competitive immunoassay. The assay includes the use of antibodies to SDMA that are specific for SDMA and that have less affinity for other arginine derivatives.

Detection of symmetrical dimethylarginine

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Falmouth, ME, United States of America

Hongzhi Xie