Jiangsu Academy of Agricultural Sciences

Grand Theravac Life Sciences (nanjing) Co., Ltd.

Jiangsu Theravac Bio-pharmaceutical Co., Ltd.

Hongying Huang

Xiaoxiao Chen

Xiaomei Ye

Hongmei Jin

Jianqiang Li

Tong Zhou

Jun Ge

Enhui Sun

Yue Gu

Honglin Sun

Ning Zhu

Jing Du

Yonglan Xi

Sulin Ren

Jiaojiao Sun

Ying Sun

Xue Zhou

Danyang Li

Cheng Yong

Yueding Xu

Zhizhou Chang

Guofeng Wu

Zhenxing Xu

Meiju Wang

Cuiling Song

Xiaoqian Zhuang

Mengjie Zheng

Sean Xiaohan Du

The present invention discloses a pharmaceutical preparation for treating hepatitis B, a preparation method and use thereof. The pharmaceutical preparation comprises a solution of hepatitis B surface antigen, further a solution of hepatitis B core antigen, and furthermore an oligodeoxynucleotide solution. The pharmaceutical preparation is free of saccharide, has a simple composition and a good antigen stability, without the adverse reactions caused by aluminum adjuvants, and shows good preservation effects in long-term stability experiments.

Pharmaceutical preparation for treating hepatitis b, preparation method therefor and use thereof

A preparation method for a combined modified straw active particulate carbon adsorption material and use of same. The preparation method for the combined modified straw active particulate carbon adsorption material comprises the following steps: 1) mixing straw powders, distilled water, a binder and a composite mineral, then pelletizing same, and then placing same in a tube furnace for pyrolysis to prepare straw particulate carbon; 2) introducing an inert gas into a modification reagent, adjusting the pH value combined and 3) soaking the straw particulate carbon into the combined modification solution for 30 min, and performing cleaning and drying, so as to obtain a combined modified straw active particulate carbon adsorption material. The combined modified straw active particulate carbon has a good adsorption effect on phosphate group in low-pollution water.

Preparation method for combined modified straw active particulate carbon adsorption material and use of same

A malic acid and KMnO4-based combined and modified cow dung biogas residue hydrochar preparation method, comprising: mixing a cow dung biogas residue with malic acid, and performing ultrasonic treatment to obtain a malic acid modified cow dung biogas residue; performing a hydrothermal reaction with KMnO4 in a high-temperature high-pressure reactor to obtain a combined and modified cow dung biogas residue hydrochar material.

Malic acid and KMnO-based combined and modified cow dung biogas residue hydrochar preparation method

Disclosed is a composition comprising: i) HBsAg, a fragment thereof, a variant thereof, or the mixture of at least two of them, ii) HBcAg1-X, a fragment thereof, a variant of the antigen or the antigen fragment, or the mixture of at least two of them, wherein X is an integer of from 149 to 183, iii) CpG-ODN, 21 bases long, which is a phosphorothioate oligonucleotide and includes two or more copies of 5'-NTCGTT-3&#x2032; motifs. The use of the composition in the treatment of HBV-infection and HBV-induced diseases, and the therapy methods of HBV-infection and HBV-induced diseases are also disclosed.

Hepatitis B vaccine

Growing community of inventors

Nanjing, China

Hongying Huang