Zhejiang University

Hongxi Zhang

Yi Zhang

Dan Wu

Ruibin Liu

Tingting Liu

Disclosed is a method and apparatus for frequency drift correction of magnetic resonance CEST imaging, and a medium and an imaging device. The method comprises the following steps: firstly, in the frequency drift correction module, exciting a target slice by using a small flip-angle radio-frequency pulse, and acquiring a single line of free induction decay signals or two lines of non-phase encoding gradient echo signals; secondly, respectively calculating a value of the main magnetic field frequency drift according to phase information and an acquisition time of the single line of free induction decay signals or the two lines of non-phase encoding gradient echo signals; then adjusting the center frequency of the magnetic resonance device in real time according to the calculated value of the main magnetic field frequency drift, and achieving the real-time correction of main magnetic field frequency drift; and finally, performing CEST imaging.

Method and apparatus for frequency drift correction of magnetic resonance CEST imaging, and medium and imaging device

The present disclosure provides a method for optimizing T1-weighted magnetic resonance imaging of infant brains. Firstly, T1 and PD maps of infant brains at 0-12 months old are collected to obtain average T1 and PD values of WM and GM of the infant brains, and infants are classified into three age groups according to the characteristics of WM and GM T1 values of the infant brains. Then, the theoretical signal strength of the WM and GM of the infant brains generated from a 3D T1-weighted imaging sequence is calculated through Bloch simulation, and a theoretical optimal TI scheme of each group is determined according to the simulated WM/GM contrast characteristics under different TIs. Finally, the theoretical optimal TI scheme is applied to a target infant brain according to the designated age group for 3D T1-weighted magnetic resonance imaging.

Method for optimizing T1-weighted magnetic resonance imaging of infant brain

A magnetic resonance CEST imaging sequence and device based on a frequency stabilization module are provided. It includes following steps: first, in the frequency stabilization module, exciting a target slice with a small-flip-angle radio frequency pulse, and collecting three lines of non-phase-encoded k-space data; second, obtaining an estimated value of the frequency drift of the main magnetic field by calculating the phase difference between the three lines of non-phase encoded k-space data; third, adjusting a center frequency of the radio frequency pulse based on the calculation result of the frequency drift of the main magnetic field, to realize a real-time correction of the frequency drift of the main magnetic field; and fourth, performing conventional magnetic resonance CEST imaging.

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Hangzhou, China

Hongxi Zhang