Gilead Sciences, Inc.

Gilead Pharmasset LLC

Gilead Sciencs, Inc.

Hongtao Liu

Lianhong Xu

Manoj C Desai

Michael L Mitchell

Randall W Vivian

Choung U Kim

John O Link

Hongyan Guo

Randall Halcomb

Jianyu Sun

James G Taylor

Richard L Mackman

Elizabeth M Bacon

James D Trenkle

William John Watkins

Hyung-Jung Pyun

Jeromy J Cottell

Aesop Cho

Scott E Lazerwith

Darryl Kato

Thorsten A Kirschberg

Winston C Tse

Eda Y Canales

Jay P Parrish

Joseph H Saugier

Michael Graupe

Matthew A Williams

Scott D Schroeder

Qi Liu

Evan S Krygowski

Kerim Babaoglu

Paul A Roethle

Ryan McFadden

Willard Lew

Allen Yu Hong

Hon Chung Hui

Norbert W Bischofberger

Yingmei Qi

Hong Yang

Gediminas J Brizgys

Paul Hrvatin

Kyla Bjornson

Sundaramoorthi Swaminathan

Xiaowu Chen

Eric Lansdon

Peter H Nelson

Zheng-Yu Yang

William A Lee

James Ming Chen

Kuei-Ying Lin

Richard Y Huang

John C Martin

Haolun Jin

Maria Fardis

Lijun Zhang

Xiaochun Han

Murty N Arimilli

Christopher P Lee

Gong-Xin He

Jianying Wang

Richard Yu

Mark L Sparacino

Jiancun Zhang

Jake Cha

Hyung-Jun Pyun

Murty N Arimili

James D Tario

Mark M Becker

Clifford Bryant

Azar Dastgah

Tanisha D Rowe

Mark Sparacino

Richard H Yu

Monoj C Desai

Radall W Vivian

Randall L Halcomb

James Taylor

The invention is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.

Antiviral compounds

The present application provides for a compound of Formula IV, or a pharmaceutically acceptable salt, solvate, and/or ester thereof, compositions containing such compounds, therapeutic methods that include the administration of such compounds, and therapeutic methods and include the administration of such compounds with at least one additional therapeutic agent.

Modulators of pharmacokinetic properties of therapeutics

The invention provides compounds and salts thereof as d herein. The invention also provides pharmaceutical compositions comprising a compound disclosed herein, processes for preparing compounds disclosed herein, intermediates useful for preparing compounds disclosed herein and therapeutic methods for treating an HIV infection, treating the proliferation of the HIV virus, treating AIDS or delaying the onset of AIDS or ARC symptoms in a mammal using compounds disclosed herein.

2-(tert-butoxy)-2-(7-methylquinolin-6-yl) acetic acid derivatives for treating AIDS

The invention provides compounds of formula (I): or a salt thereof as described herein. The invention also provides pharmaceutical compositions comprising a compound of formula (I), processes for preparing compounds of formula (I), intermediates useful for preparing compounds of formula I and therapeutic methods for treating the proliferation of the HIV virus, treating AIDS or delaying the onset of AIDS or ARC symptoms in a mammal using compounds of formula (I). 

2-quinolinyl-acetic acid derivatives as HIV antiviral compounds

Naphthalene acetic acid derivatives against HIV infection

The present application provides for a compound of Formula I, or a pharmaceutically acceptable salt, solvate, and/or ester thereof, compositions containing such compounds, therapeutic methods that include the administration of such compounds, and therapeutic methods and include the administration of such compounds with at least one additional therapeutic agent.

The invention provides compounds of formula (I): or a salt thereof as described herein. The invention also provides pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula (I), intermediates useful for preparing compounds of formula I and therapeutic methods for treating the proliferation of the HIV virus, treating AIDS or delaying the onset of AIDS or ARC symptoms in a mammal using compounds of formula (I). 

Naphth-2-ylacetic acid derivatives to treat AIDS

Compounds of formula I': or salts thereof are provided. Pharmaceutical compositions comprising a compound of formula I&#x2032;, processes for preparing compounds of formula I&#x2032;, intermediates useful for preparing compounds of formula I&#x2032; and therapeutic methods for treating the proliferation of the HIV virus, treating AIDS or delaying the onset of AIDS or ARC symptoms in a mammal are also provided.

Therapeutic compounds

The present application provides for a compound of formula I, or a salt thereof, compositions containing such compounds, therapeutic methods that include the administration of such compounds, and therapeutic methods that include the administration of such compounds with at least one additional therapeutic agent. 

Inhibitors of cytochrome P450

Compounds disclosed herein including compounds of formula I': and salts thereof are provided. Pharmaceutical compositions comprising compounds disclosed herein, processes for preparing compounds disclosed herein, intermediates useful for preparing compounds disclosed herein and therapeutic methods for treating an HIV infection using compounds disclosed herein are also provided.

Growing community of inventors

Cupertino, CA, United States of America

Hongtao Liu