Bausch-lomb Incorporated

Hongna Wang

Brent Whitehead

Michael Hall

Stephen R Davio

Gregory L McIntire

Shazad Suchit

Jon Summersett

Erning Xia

Susan E Burke

Praveen Tyle

Eric Phillips

Srini Venkatesh

Zora T Marlowe

Pramod Kumar Gupta

Susan E Norton

Lynne Brunner

Keith W Ward

Paramita Bandyopadhyay

Matthew Scott Jonasse

Zora Teresa Marlowe

An aqueous contact lens solution comprising less than 100 ppm of a tertiary amine oxide of general formula 

Contact lens solution with a tertiary amine oxide

A polymorph of brimonidine pamoate having the formula exhibits characteristics disclosed herein. The polymorph is included in a composition, device, or implant for use in the treatment or control of elevated intraocular pressure or in the neuroprotection of components of a neurological tissue to prevent progressive degeneration of such components. In particular, such a composition, device, or implant can be used to provide neuroprotection to cells and components of the optic nerve system.

Polymorphs of brimonidine pamoate

A brimonidine pamoate polymorph exhibits characteristics disclosed herein, wherein the brimonidine pamoate has the following formula  The polymorph is included in a composition, device, or implant for use in the treatment or control of elevated intraocular pressure or in the neuroprotection of components of a neurological tissue to prevent progressive degeneration of such components. In particular, such a composition, device, or implant can be used to provide neuroprotection to cells and components of the optic nerve system.

Compositions for treating, reducing, ameliorating, or preventing infections comprise a fluoroquinolone having Formulae I-VIII and an additional anti-infective agent. Methods for treating, reducing, ameliorating, or preventing such infection use such compositions. Such compositions and methods can be effective against mixed types of pathogens including certain antibiotic-resistant microbial pathogens found in such infections.

Compositions and methods for treating, reducing, ameliorating, or preventing infections

A brimonidine (5-bromo-6-(2-imidazolidinylideneamino)quinoxaline) pamoate polymorph exhibits characteristics disclosed herein. The brimonidine pamoate polymorph is included in a composition, device, or implant for use in the treatment or control of elevated intraocular pressure or in the neuroprotection of components of a neurological tissue to prevent progressive degeneration of such components. In particular, such a composition, device, or implant can be used to provide neuroprotection to cells and components of the optic nerve system.

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Fairport, NY, United States of America

Hongna Wang