Corning Incorporated

Other

Hongming Wang

Marie D Bryhan

Zhong-he Shen

Oliva V LaChance

Paul Ernest Gagnon, Jr

Paul E Gagnon

John Stephen Peanasky

Gregory Roger Martin

Allison Jean Tanner

Ye Fang

Joydeep Lahiri

Terry T Goodrich

Jun Xi

A method of producing an improved cell growth surface and cell attachment surface. According to the present invention, a polymer article is molded at temperature in excess of 550&#xb0; F. at the injection tip. After allowing the part to cool, a stream of plasma comprised of activated gaseous species generated by a microwave source is imparted on the article. This stream is directed at the surface of a polymer substrate in a controlled fashion such that the surface is imparted with attributes for cell adhesion superior to those of untreated polymer or polymer treated by other methods.

Method of making enhanced cell growth surface

Disclosed is a cell culture article including: a substrate; a tie-layer attached to at least the substrate; and a bio-compatible layer attached to at least the tie layer, the bio-compatible layer having been obtained from surface oxidation of a polymer layer. Also disclosed are methods for making the cell culture article and methods for performing an assay of a ligand with the article.

Cell culture article and methods thereof

A product exhibiting an improved cell growth surface and cell attachment. According to the present invention, a stream of plasma is comprised of activated gaseous species generated by a microwave source. This stream is directed at the surface of a polymer substrate in a controlled fashion such that the surface is imparted with attributes for cell adhesion far superior to that of untreated polymer or polymer treated by other methods.

Cell growth surface on a polymeric substrate

A multiwell plate is described that is used for assaying samples and is made from a plastic upper plate which forms the sidewalls of one or more wells and a glass lower plate which forms the bottom walls of the wells. The plastic upper plate and glass lower plate are attached and bound to one another by an enhanced adhesive. The enhanced adhesive includes an adhesive mixed with an additive that interacts with the adhesive, the plastic upper plate and the glass bottom plate in a manner that strengthens a bond between the plastic upper plate and the glass lower plate. Also described herein is a method for making such multiwell plates.

Multiwell plate having transparent well bottoms

A method, apparatus and product for producing an advantaged cell growth surface. According to the present invention, a stream of plasma is comprised of activated gaseous species generated by a microwave source. This stream is directed at the surface of a polymer substrate in a controlled fashion such that the surface is imparted with attributes for cell adhesion far superior to that of untreated polymer or polymer treated by other known methods.

Method for creating a cell growth surface on a polymeric substrate

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Kennebunk, ME, United States of America

Hongming Wang