Sunshine Guojian Pharmaceutical (shanghai) Co., Ltd.

Zlip Holding Limited

Sunshine Guojian Pharmaceutical (shanghai) Co., Lt

Honghai Gao

Jie Zhao

Chenghai Zhang

Jinlin Guo

Wei Dang

Lingqiao Zhu

Lei Shi

Jing Li

Yan Yang

Le Zhao

Zhenping Zhu

Haomin Huang

Yangsheng Qiu

Jianhe Chen

Xu Fang

Lin Ma

Hongtao Lu

Fenglan Wu

Shou Li

James S Yan

Disclosed herein are antigen binding units that specifically bind to CD47. Further disclosed herein are polynucleic acids encoding said antigen binding units, vectors comprising said polynucleic acids, and hybridomas and host cells comprising said vectors. Further provided herein are methods for inducing phagocytosis of CD47-expressing cells.

CD47 antigen binding unit and uses thereof

An anti-human PD-1 monoclonal antibody, and a preparation method therefor and an application thereof. The anti-human PD-1 monoclonal antibody has good bioactivity, can effectively bind with an extracellular region of a human PD-1 protein receptor, and can effectively seal PD-1 protein at protein level and cellular level and block the binding of the PD-1 protein with a ligand PD-L1, thereby effectively enhancing immunity. The monoclonal antibody can be applied independently or jointly with other antitumor drugs to tumor immunotherapy and the diagnosis and screening of patients with PD-L1 positive tumors; and the monoclonal antibody has a promising prospect in the preparation of drugs for treating tumors, resisting autoimmune diseases and the like.

Anti-PD-1 monoclonal antibody, and preparation method therefor and application thereof

An anti-human IL-17A monoclonal antibody, the preparation method, and the use thereof are provided. The anti-human IL-17A monoclonal antibody can specifically bind to human IL-17A and has a good effect for inhibiting the secretion of inflammatory cytokines, such as IL-6 and the like by means of various cell lines induced by IL-17A, and can be used for preparing drugs for treating diseases involving immune-medicated inflammatory responses.

Anti-human interleukin-17A monoclonal antibody

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Shanghai, China

Honghai Gao