Shaanxi University of Science and Technology

Shaanxi Rongna Material Technology Co., Ltd.

Shaanxi Environmental Protection Research Inst.

Hongbo Li

Dong Li

Zhen Wang

Xiaohui Zhou

Min Zhang

Dan Xu

Liangbin Hu

Yifan Lei

Haizhen Mo

Jundong Wang

Qingyi Wang

Feng Ji

Zhenbin Liu

An application of a hydrogel in the preparation of products for the treatment of bacterial infection is disclosed. Ferrous ion was used in the antibacterial activity test ofand showed a strong bactericidal effect, which the survival rate ofis less than 0.001%, as well as the survival rate of methicillin-resistant(MRSA) was less than 0.01%. Ferrous ion hydrogel was used for the treatment of keratitis and skin wound infection. Ferrous ion hydrogel for the treatment of keratitis and skin wound infection, which can significantly reduce the risk of pulmonary MRSA infection, prevented the dissimilation of MRSA to the lung, and alleviated systemic inflammation in the body in a timely and effective manner, revealing the therapeutic potential of ferrous compounds for treatment ofinfections, including MRSA.

Application of a hydrogel in the preparation of products for the treatment of bacterial infections

An electrospun nanofiber membrane and a method for preparing the electrospun nanofiber membrane are provided to solve problems of poor mechanical properties, short service life, poor uniformity and consistency of orientation of fibers and poor stability of fiber networks in current electrospun composite nanofiber materials. The electrospun nanofiber membrane is prepared by spinning solution through a high-voltage electrospinning device. The spinning solution is blending solution of regenerated silk fibroin:polyvinyl alcohol:polylactic acid with a mass ratio being 75-85:10-20:5 dissolved in a mixed solvent of trifluoroacetic acid and dichloromethane with a volume ratio being 7:3. The method establishes a reasonable mass ratio parameter of the regenerated silk fibroin, the polyvinyl alcohol and the polylactic acid to blending spinning to improve spinnability of silk fibroin, as well as prepare the electrospun composite nanofiber membrane with good mechanical properties.

Electrospun nanofiber membrane and method for preparing electrospun nanofiber membrane

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Xi'an, China

Hongbo Li