Mei Pharma, Inc.

Agency for Science, Technology and Research

S'bio Pte Ltd

Hong Yan Song

Yong Colin Zou

Eric T Sun

DiZhong Chen

Niefang Yu

Xiaodong Zhou

Ping Bai

Lin Wu

Anton Sadovoy

Ten It Wong

Kanda Sangthongpitag

Yong Zou

Yong Blk 5 Hong Leong Garden Condo Zou

The present invention relates to hydroxamate compounds which are inhibitors of histone deacetylase. More particularly, the present invention relates to benzimidazole containing compounds and methods for their preparation. These compounds may be useful as medicaments for the treatment of proliferative disorders as well as other diseases involving, relating to or associated with dysregulation of histone deacetylase (HDAC).

Benzimidazole derivatives: preparation and pharmaceutical applications

There is method for detecting the presence or absence of a target analyte in a sample comprising the steps of: allowing an inorganic fluorescent particle to conjugate with a detection biomolecule that is bound to said target analyte, if present in said sample, said target analyte additionally being bound by a capture biomolecule immobilized on or within a nanostructure; and detecting the fluorescence emitted by said inorganic fluorescent particle, said nanostructure being capable of generating a surface plasmon resonance effect when excited by a light source to substantially increase the fluorescence emitted by said inorganic fluorescent particle, wherein the detected fluorescence indicates the presence of said target analyte in said sample.

Method for detecting a target analyte

Growing community of inventors

Singapore, Singapore

Hong Yan Song