Hoffmann-la Roche Inc.

Merck Sharp + Dohme Corp.

Chinese Academy of Sciences

Alcatel

Shanghai Zhenchun Cosmetics Co., Ltd.

F. Hoffmann-la Roche Ag

Hong Shen

Taishan Hu

Wei Zhu

Lei Guo

Mingwei Zhou

Weixing Zhang

Fabian Dey

Fa-Xiang Ding

Xingchun Han

Roger David Norcross

Hans Hilpert

Guido Galley

Philippe Pflieger

Kun Liu

Dong-Ming Shen

Zhicai Wu

Jason M Cox

Richard Thomas Beresis

Xuefei Tan

Anthony K Ogawa

Xudong Wang

Sabine Kolczewski

Konrad H Bleicher

Peter J Sinclair

Steven L Colletti

Alexander Alanine

Zhiwei Zhang

Subharekha Raghavan

Robert J DeVita

Darby Schmidt

Song Feng

Lu Gao

Yan Chen

Jun Wu

Li Ping Wang

Hongying Yun

Jingjing Liu

Jinlong Jiang

Alexander Mayweg

Lisha Wang

Rui Liang

Li Wang

James R Tata

Zhi-Cai Shi

Guang Yang

Chungen Liang

Yongfu Liu

Chao Li

Linda Brockunier

Ge Zhu

Dongdong Chen

Xiao Ding

Zhisen Zhang

Xianfeng Lin

Buyu Kou

Shixiang Yan

Yimin Hu

Houguang Shi

Haixia Liu

Junhao Chu

Guolong Wu

Theodor Stoll

Buelent Kocer

Giuseppe Cecere

Bernhard Fasching

Yuguang Wang

Ping Lan

Changhe Qi

Carsten Kroll

Amal Wahhab

Christine Yang

Dwight MacDonald

Adrian Schaeublin

Helmut Thomas

Alejandro Crespo

John Qiang Tan

Zhongxiang Sun

Hongtao Xu

Zongxing Qiu

Rudrajit Mal

Ge Zou

Min Shu

Ellen K Vande Bunte

Xiaohua Cui

John E Stelmach

Dan Zhao

Guozhi Tang

Jian Guo

Isabel Najera

Chengang Zhou

Kun Miao

Jianguo Chen

Keith Rosauer

Feng Zhou

Hong Dong Chu

Xiaoqing Wang

Xinning Huang

Wenming Chen

A cosmetics container includes a housing, a bottom sleeve, an inner bottom, a lower elastic element, a button, and a middle sleeve thereof. The pressing area is provided on the housing. The bottom sleeve is provided inside of the housing, and the inner bottom is provided inside of the bottom sleeve. The lower elastic element is provided inside of the bottom sleeve and is located at a lower surface of the inner bottom. The middle sleeve is provided inside of the housing and is located at an upper surface of the inner bottom. The middle sleeve is provided with an upper elastic element, which abuts against the button. The button includes an upper rim, a pressing piece, and a lower rim thereof. The pressing piece is located in the middle between the upper rim and the lower rim and is provided at the pressing area.

Cosmetics container

The invention provides novel compounds having the general formula: wherein R, R, R, R, R, R, X, Y, W and n are as described herein, compositions including the compounds and methods of using the compounds.

6-fused heteroaryldihydropyrimidines for the treatment and prophylaxis of hepatitis B virus infection

The present invention relates to compounds of formula (I), wherein R, R, Rand Rare as described herein, and their pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.

Pyrazolopyridine compounds for the treatment of autoimmune disease

The present invention relates to compounds of formula (Ib), wherein Rto R, M and L are as described herein, and their pharmaceutically acceptable salt, enantiomers and diastereomers thereof, and compositions including the compounds and methods of using the compounds.

Tricyclic compounds for the treatment of cancer

The present invention relates to compounds of formula (I), wherein Rto R, m and n are I a described herein, and their pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.

Tetrahydro-1H-pyrazino[2,1-a]isoindolylquinoline compounds for the treatment of autoimmune disease

The present invention provides flavone derivatives having the general formula (I) which are useful for the treatment of Hepatitis B Virus infection (HBV). The compounds act as cccDNA (covalently closed circular DMA) inhibitors.

Flavone compounds for the treatment and prophylaxis of hepatitis B virus disease

The present invention provides compounds of formula (I)

Peptide macrocycles against

The present disclosure relates to the field of preparation of compound semiconductor nanomaterials, and in particular to a method for in-situ modification of mercury quantum dots in a traditional thermal injection process. It is characterized in that, in the traditional thermal injection process for synthesis of HgTe quantum dots, after a certain reaction time, a low boiling point polar solvent that is incompatible with a reaction solvent is rapidly injected, so that an interfacial separation of two liquid phases occurs in a mixed reaction, and then a selective crystal oriented surface modification is conducted on surfaces of mercury quantum dots.

Method for in-situ modification of mercury quantum dots in traditional thermal injection process

Disclosed are a mercury cadmium telluride-black phosphorus van der Waals heterojunction infrared polarization detector and a preparation method thereof. The structure of the detector from bottom to top comprises a substrate, a mercury cadmium telluride material, an insulating layer, a two-dimensional semiconductor black phosphorus, and metal electrodes. First, growing the mercury cadmium telluride material on the substrate, removing part of the mercury cadmium telluride by ultraviolet lithography and argon ion etching, filling with aluminum oxide as the insulating layer using an electron beam evaporation method, transferring the two-dimensional semiconductor material black phosphorus at the junction of mercury cadmium telluride and an insulating layer assisted by a polypropylene carbonate film, and preparing the metal source-drain electrodes by electron beam lithography technology combined with the lift-off process to form the mercury cadmium telluride-black phosphorus van der Waals heterojunction infrared polarization detector.

Mercury cadmium telluride-black phosphorous van der waals heterojunction infrared polarization detector and preparation method thereof

The present invention relates to compounds of formula (I), ab (I), wherein R1 to R3 and L are as described herein, and their pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.

Heteroaryl heterocyclyl compounds for the treatment of autoimmune disease

The present invention relates to compounds of formula (I), wherein R, Rand Rare as described herein, and their pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds as antagonist of TLR7 and/or TLR8 and/or TLR9 in the treatment of autoimmune diseases as well as auto-inflammation diseases. 

Cyclic amidine compounds for the treatment of autoimmune disease

The present invention relates to compounds of the formula (I), 

Methods of synthesizing pyrazine compounds

A ferroelectric domain regulated optical readout mode memory and a preparing method thereof. The memory has such a structure that a two-dimensional semiconductor and a ferroelectric film layer are sequentially arranged on a conductive substrate. The method for preparing the memory includes the steps of preparing the two-dimensional semiconductor on the conductive substrate, preparing a ferroelectric film, then writing a periodic positive-reverse domain structure into the ferroelectric film on the two-dimensional semiconductor by using a piezoresponse force microscopy technology, and regulating a photoluminescent intensity of the two-dimensional semiconductor WSby using a ferroelectric domain. A fluorescent picture taken by a fluorescent camera shows light and dark areas corresponding to polarization directions, the light and dark areas represent an on state ('1') and an off state ('0') of the memory respectively, and accordingly the purpose of storage is achieved.

Ferroelectric domain regulated optical readout mode memory and preparing method thereof

The present invention provides compounds of formula (I) 

Peptide macrocycles against Acinetobacter baumannii

An ultra-broad spectrum detector integrated with functions of a two-dimensional semiconductor and a ferroelectric material, where the device includes a substrate, a two-dimensional semiconductor, a source electrode, a drain electrode, a ferroelectric material and a gate electrode; the two-dimensional semiconductor, the source electrode and the drain electrode are arranged on an upper surface of the substrate, and the source electrode and the drain electrode are respectively arranged at two ends of an upper surface of the two-dimensional semiconductor; two sides of the two-dimensional semiconductor are respectively connected with the lower-layer metal of the source electrode and the lower-layer metal of the drain electrode; the ferroelectric material is arranged on the upper surfaces of the two-dimensional semiconductor, the source electrode and the drain electrode; and the lower surface of the gate electrode is connected with the upper surface of the ferroelectric material.

Ultra-broad spectrum detector integrated with functions of two-dimensional semiconductor and ferroelectric material

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Shanghai, China

Hong Shen