Korea Institute of Science and Technology

Snu Rdb Foundation

Hong Ryul Ahn

Joo Young Lee

Jungyeob Ham

Heonjoong Kang

Cheol-Ho Pan

Eun Ha Lee

Kyungsu Kang

Yongsoo Choi

Hee Ju Lee

Jung-Seok Yang

Kyung A Kim

Suk-Woo Kang

Youngwoo Song

Young Hee Park

Jae-In Eom

Disclosed is a method for preventing, improving and/or treating cornea damage or a corneal disease, including administering an effective amount of an extract of a persimmon tree for preventing, improving or treating cornea damage to a subject in need thereof. The extract may be a persimmon leaf extract and the extract is effective in suppressing inflammation of the cornea and protecting corneal cells.

[object Object]

Provided are a production method for a potassium organotrifluoroborate compound having a hydroxyl group, and a novel potassium organotrifluoroborate compound having a hydroxyl group. The production method is advantageous in that a potassium organotrifluoroborate compound can be produced in a single reaction without recourse to a process of isolating and purifying an intermediate. The novel potassium organotrifluoroborate compound having a hydroxyl group is useful as a reactant which is widely used in the total synthesis of physiologically active natural products and diverse organic synthesis reactions including halogen substitution reactions, 1,2- and 1,4-addition reactions using a rhodium (Rh) catalyst, and Suzuki coupling reactions using a palladium (Pd) catalyst.

Potassium organotrifluoroborate derivative and a production method therefor

Growing community of inventors

Gangneung-si, South Korea

Hong Ryul Ahn