Proteus Gmbh

Proteus S.a.

Universite De Berne

Hong-Khanh Nguyen

Christian Weitemeyer

Fabrice Lefevre

Jean-Louis Reymond

Burghard Grüning

Denis Wahler

Geoffrey Hills

Thomas Veit

Olivier Favre-Bulle

Gilles Ravot

Frabrizzio Badalassi

Fabrizzio Badalassi

This invention has as its object a method for releasing a product by subjecting a compound of Formula (II'): R&#x2032;R&#x2032;(HX)C-C(YH)R&#x2032;R&#x2032;to a chemical oxidation that cleaves the bond C-Cto obtain the product. In the compound of Formula (II&#x2032;): R&#x2032;to R&#x2032;, which are identical or different, correspond to a hydrogen atom, a substituted or unsubstituted alkyl group, or a substituted or unsubstituted functional group; X and Y, which are identical or different, are an oxygen atom, a sulfur atom, or an amine of Formula &#x2014;NRR, wherein Ris a hydrogen atom, an alkyl group, or a substituted or unsubstituted aryl group, and Ris not a hydrogen atom. The invention also has as its object a method for releasing a product that comprises, before the chemical oxidation stage, a first step for preparing the compound of Formula (II&#x2032;). The released product can be a volatile molecule or an active substance or else a specific product. The invention also relates to a method for detecting the released product as well as its applications, in particular for detecting catalytic or enzymatic activities.

Method for releasing a product comprising chemical oxidation, method for detecting said product and uses thereof

The present invention relates to a newly identified hydrolase from thermophilic microorganisms having thermostable properties, and more specifically, to a novel thermostable hydrolase showing high activity at high temperatures.

Thermostable esterases from thermophilic bacteria

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Nimes, France

Hong-Khanh Nguyen