Other

Samsung Electronics Co., Ltd.

Eyegene Inc.

Kim, Hong-Jin

Hong-Jin Kim

Hyoung Jin Kim

Kun-Tack Lee

Byoung-ho Kwon

Jae-Kwang Choi

Yujin Lee

Yang-Je Cho

Jin-Wook Jang

Na Gyong Lee

Sol Han

Keon-Sik Seo

Kwang Sung Kim

Kyungsook Han

Wootaek Kim

Young-Ki Shon

Jae-Wook Jung

Hyoung-Jin Kim

Joon-Mok Han

Provided is a method of purifying human papillomavirus (HPV) L1 proteins with high purity and high efficiency. According to the purification method, a purification purity and yield of HPV L1 proteins can be considerably increased when heating/chilling is formed by treating a cell homogenate with a reducing agent. In addition, VLPs of the HPV L1 protein purified by the purification method have excellent antigenicity and immunogenicity.

High efficiency method for purifying human papillomavirus virus-like particles

The present invention relates to a pharmaceutical vaccine composition for a human cervical cancer, comprising: (a) (i) a L1 virus-like particle (VLP) of human papillomavirus (HPV) type 16, a L1 VLP of HPV type 18, or a combination thereof; and (ii) a deacylated non-toxic lipooligosaccharide (LOS); and (b) a pharmaceutically acceptable carrier; and a method for preparing a human papillomavirus (HPV) L1 virus-like particle (VLP). The pharmaceutical vaccine composition of the present invention is in both Th1-type immune response (cellular immunity) and Th2-type immune response (humoral immunity) against HPV more excellent than Cervrix&#x2122; and Gardasil&#x2122;, exhibiting a superior efficacy as a vaccine for a human cervical cancer.

Vaccine for cervical cancer

A pad conditioning disk, a pre-conditioning unit, and a CMP apparatus having the same are provided. The pad conditioning disk includes a base in which mountain-type tips and valley-type grooves are repeatedly connected to each other, and a cutting layer formed on the base layer. The cutting layer including conditioning particles deposited on surfaces of the tips and grooves. A surfaces roughness of conditioning particles deposited on the surfaces of the tips is less than a surface roughness of conditioning particles deposited on the surfaces of the grooves.

Chemical mechanical polishing apparatus having pad conditioning disk and pre-conditioner unit

Disclosed is a visualization method of RNA pseudoknot structures. The method of the invention comprises the steps of setting criteria required for visualizing RNA pseudoknots, setting structural elements and data structures for representing a whole RNA structure containing pseudoknots, determining an input format for visualization and a drawing order of the structure, determining connectivity relations between regular loops and stems in the structure and between pseudoknot loops and stems in the structure, calculating radii of the regular loop and the PK loop, calculating coordinates of bases in the regular loops, setting internal angles of the PK loops, calculating startAngles of the regular loops and angles of the stem, determining positions of the pseudoknots in the PK loops, and drawing the pseudoknots and the whole RNA structure containing the pseudoknots.

Visualization method of RNA pseudoknot structures

Growing community of inventors

Seoul, South Korea

Hong-Jin Kim