Basf Se Corporation

Symrise Ag

Nutrinova Nutrition Specialties & Food Ingredients Gmbh

B.r.a.i.n. Biotechnology Research and Information Network Ag

Henkel Ag & Company, Kgaa

Viscum Ag

Biotechnology Research and Information Network Ag

Holger Zinke

Michael Krohn

Karl-Heinz Maurer

Beatrix Kottwitz

Thomas Subkowski

Claus Bollschweiler

Jens Wittenberg

Heiko Oertling

Walter Kuhn

Gabriele Vielhaber

Jürgen Eck

Erich Dilk

Roland Breves

Ingo Wöhrle

Patrick Lorenz

Esther Gabor

Hans Lentzen

Claudia Gömann

Andreas Ernst

Antje Köhler

Christian Köpsel

Christian Ewering

Antje Pfeiffer

Jörg Mampel

Markus Matuschek

Alice Kleber

Micheal Krohn

Juergen Eck

Axel Baur

Ingo WÖHRLE

Claudia GÖMANN

Martin B Jager

Jurgen Eck

The present invention relates to the use of compounds which are capable of producing a cooling sensation when they are brought into contact with the human body. In particular, the present invention relates to the use of compounds modulating TRPM8, and optionally to the use of compounds selectively exhibiting agonist activity at the TRPM8 channel. Such compounds have applications in many fields, particularly in oral and personal hygiene products and foodstuffs, but also in pharmaceutical composition products, cosmetics, textile products and packaging products. The present invention further relates to products containing such compounds and to the medical use of such compounds.

Small molecule modulators of the cold and menthol receptor TRPM8

The invention relates to novel modulators of the cold menthol receptor TRPM8, to a method for modulating the TRPM8 receptor using said modulators; to the use of the modulators for induction of cold sensation; and to objects and means produced using said modulators.

Detection and use of low molecular-weight modulators of the cold-menthol receptor TRPM8

The present invention primarily relates to the use of trans-tert-butyl cyclohexanol as skin irritation-reducing agent as well as compositions (formulations) having a skin irritation-reducing action comprising trans-tert-butyl cyclohexanol as skin irritation-reducing agent.

Compositions comprising trans-tert-butyl cyclohexanol as skin irritation-reducing agent

The present invention relates to antimicrobially active &#x3c9;-cyclohexylalkan-1-oles of the following formula (I), to a method for producing said compounds and to the use thereof as antimicrobial agents for treating body odor, whereinRto Rindependently of one another denote hydrogen or a linear or branched alkyl radical having 1 to 12 carbon atoms,Rand Rindependently of one another denote hydrogen, a linear or branched alkyl radical having 1 to 6 carbon atoms or a linear or branched alkoxy radical having 1 to 4 carbon atoms, andx is 0 or 1,wherein preferably the total number of carbon atoms in Rto Ris 18 or less.

Omega-cyclohexylalkan-1-oles and use thereof as antimicrobial actives to combat body odor

The present invention relates to a screening system for modulators of GPCRs. Further it relates to recombinant vector systems for the heterologous expression of heterodimeric g-protein coupled receptors (GPCRs) in eukaryotic host cells. Preferably the functional expression of engineered GPCRs for the perception of sweet and L-amino acid taste or more preferably the use of these receptors for the identification of functional ligands is also encompassed.

Optimized human T1R2 nucleic acid molecule

Optimized human T1R3 nucleic acid molecule

The invention relates to a new glycosyl hydrolases with an amyloltic activity and nucleic acids coding for said gylcosyl hydrolases, A PCR-based method for identifying and preparing new gylcosyl hydrolases from metagenome DNA and several possible technical uses for such glycosyl hydrolases with an amylolytic activity. Washing and cleaning products containing such enzymes, and methods and possible uses corresponding thereto are particularly interesting.

Glycosyl hydrolases

Growing community of inventors

Heppenheim, Germany

Holger Zinke