Solvay Pharmaceuticals, Gmbh

Abbott Products Gmbh

Holger Sann

Jochen Antel

Ulf Preuschoff

Samuel David

Reinhard Brueckner

Daniel Jasserand

Uwe Schoen

Michael Weske

Christian Eeckhout

Dania B Reiche

Johannes Hebebrand

Michael Wurl

Michael Firnges

Peter Eickelmann

Harald Waldeck

Peter-Colin Gregory

Uwe Reinecker

Reinhard Brückner

Dania Reiche

A method of treating or inhibiting non-digestive tract derived abdominal disorders associated with pain, in particular interstitial cystitis, chronic pelvic pain syndrome and/or abdominal pain associated with endometriosis, in a patient in need thereof, by administering to the patient a pharmaceutically effective amount of a 5-HTreceptor antagonist, in particular cilansetron, or a pharmacologically compatible derivative thereof, such as a salt and/or a solvates.

Method of treating or inhibiting a non-digestive tract derived abdominal disorder associated with pain using a 5-HT, receptor antagonist

4-substituted 1-amidomethylcarbonyl-piperidine compounds having motilin-agonistic properties and their acid addition salts, pharmaceutical compositions containing these compounds, processes and intermediate products for the preparation of these compounds, and methods of treatment utilizing these compounds.

1-amidomethylcarbonyl-piperidine compounds, methods and intermediate products for the production thereof and pharmaceutical formulations containing said compounds

3-cyanonaphthalene-1-carboxylic acid perhydroxyalkylmethyl-piperazine compounds of formula I which are antagonistic to tachykinin receptors, pharmaceutical compositions containing such compounds, methods of using such compounds for the treatment and/or inhibition of various diseases and disorders, processes for preparing such piperazine compounds, and intermediate products of these processes.

NK1 and NK2-antagonists and compositions and methods of using the same

N-sulfamoyl-N'-benzopyranpiperidine compounds of formula I and their physiologically acceptable acid addition salts, pharmaceutical compositions comprising them, processes for their preparation, and their use for the treatment and/or inhibition of glaucoma, epilepsy, bipolar disorders, migraine, neuropathic pain, obesity, type II diabetes, metabolic syndrome, alcohol dependence, and/or cancer, and related concomitant and/or secondary diseases or conditions 

N-sulfamoyl-N'-benzopyranpiperidine compounds and uses thereof

A method for the discovery of compounds suitable for the treatment and/or prophylaxis of obesity, in which the ability of the test compounds to inhibit de novo lipogenesis in mammals and/or man is determined. The use of compounds which are capable of inhibiting de novo lipogenesis in mammals, and which are substantially free of effects directed towards the CNS, for the preparation of pharmaceutical compositions for the treatment and/or prophylaxis of obesity, as well as for the treatment and/or inhibition of obesity, are also described.

Method of preparing pharmaceutical compositions

Method of treating or inhibiting obesity

Method of identifying compounds suitable for treatment and/or prophylaxis of obesity

1-&lsqb;1-(hetero)aryl-1-perhydroxyalkylmethyl&rsqb;-piperazine compounds, process for their preparation and pharmaceutical compositions containing them

N-triazolylmethyl-piperazine compounds with neurokinin-receptor antagonist activity

The use of moxonidine or a physiologically compatible acid addition salt thereof for the treatment and/or inhibition of functional gastrointestinal disturbances or illnesses in the region of the lower intestinal tracts, particularly for the treatment and/or inhibition of abdominal visceral pain which accompanies them, and the preparation of pharmaceutical compositions suitable for this treatment are is described. The functional disturbances and illnesses of the lower intestinal tracts which can be treated according to the invention are known in particular as irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD), which generally also include visceral pain as one of their symptoms.

Method of treating or inhibiting functional disturbances or illnesses of the lower intestinal tracts, particularly abdominal visceral pain which accompanies them

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Hannover, Germany

Holger Sann