Carl Zeiss Meditec Ag

Holger Matz

Christoph Hauger

Marco Wilzbach

Stefan Saur

Anja Seiwert

Markus Seesselberg

Xing Wei

Joachim Steffen

Christian Voigt

Delbert Peter Andrews

Hendrik Burwinkel

Nancy Hecker-denschlag

Oliver Findl

Nino Hirnschall

Peter Reimer

Roland Guckler

Artur Hoegele

Helge Jess

Artur Högele

Carolin Schiele

Selamawit Getachew Kelemu

Christoph Backhaus

Benjamin Sorg

The invention relates to a computer-implemented method and a corresponding system for a machine-learning-supported determining of refractive power for a measure for correcting the eyesight of a patient. The method involves providing a scan result of an eye, wherein the scan result represents an image of an anatomical structure of the eye. The method also involves supplying the scan result as input data to a first machine-learning system in the form of a convolutional neural network, and using output values of the first machine-learning system as input data for a second machine-learning system in the form of a multi-layer perceptron, and a target refraction value for the second machine-learning system is used as an additional input value for the second machine-learning system. Finally, the method involves determining parameters for the measure for correcting the eyesight of a patient via an immediate and direct cooperation of the first machine-learning system and the second machine-learning system.

Machine-learning-based determining of refractive power for measures for correcting eyesight from OCT images

An eye surgery surgical system includes a visualization device for visualizing the position of at least one trocar point for a trocar on the sclera of a patient's eye. The trocar serves to introduce a surgical instrument configured for surgical interventions on the fundus of the patient's eye into the patient's eye. The eye surgery surgical system also includes a computer unit which is configured to provide the position of the at least one trocar point to the visualization device. Here, the computer unit contains a trocar point computation routine configured to calculate the position of the at least one trocar point from the location of at least one surgical site in a model of the patient's eye and from geometric data relating to at least one surgical instrument introducible into the patient's eye through the trocar.

Eye surgery surgical system and computer implemented method for providing the position of at least one trocar point

The invention relates to a computer-assisted method for position determination for an intraocular lens supported by machine learning. The method comprises providing a scan result for an eye. The scan result here represents an image of an anatomical structure of the eye. The method further comprises use of a trained machine learning system for the direct determination of a final location of an intraocular lens to be fitted, wherein digital data of the scan of the eye is used as the input data for the machine learning system.

Machine-learning based IOL position determination

Provided is to a system with an interface for providing visualization data for visualizing at least one section of a patient's eye, comprising an OCT device for capturing OCT scanning data by scanning the section of the patient's eye by means of an OCT scanning beam and comprising a computer unit for processing the OCT scanning data into the visualization data within the scope of an image rectification algorithm, which is designed to output the visualization data at the interface. The computer unit contains a view generation algorithm for calculating image data in relation to a view of a reference object arranged in the section of the patient's eye from geometry data about the reference object fed to the view generation algorithm and from the OCT scanning data obtained in relation to the reference object, wherein the computer unit has an algorithm control routine which specifies the image rectification algorithm and determines the image rectification algorithm from the image data of the view of the reference object calculated in the view generation algorithm and from OCT scanning data obtained in relation to the reference object by scanning the section of the patient's eye.

System for providing visualization data for visualizing at least one section of a patient's eye from oct scanning data, and computer-implemented method and computer program

The invention relates to an arrangementwith an OCT devicefor scanning an object region volumearranged in an object regionwith an OCT scanning beam, comprising an itemwhich has a sectionthat is arrangeable in the object regionand is localizable in the object region volumeby means of the OCT device, and having a computing unitconnected to the OCT deviceand having a computer program for determining a 3-D reconstruction of the object region volumeand determining the location of the portion of the objectin the object region volumeby processing OCT scan information obtained with the OCT deviceby scanning the object region volume. According to the invention, the computer program has a calculation routine for determining a target area in the 3-D reconstruction of the object region volume, which routine determines a reference variable for the objectfor the target area. The computer program contains a path planning routine that uses a criterion to calculate an optimal path for objectto the target spatial position, the criterion being a shadow measure that quantifies the occurrence of shadows caused by objectin the calculated 3-D reconstruction. The invention also relates to a computer program and a method for determining a 3-D reconstruction of an object region volumein an object region

Assembly comprising an OCT device for ascertaining a 3D reconstruction of an object region volume, computer program, and computer-implemented method for same

A method of determining at least one selection parameter for selecting an intraocular lens to be inserted into an eye; the method comprises reading, by a data processing system, data indicative of an axial position of at least a portion of an anterior surface of an at least partially empty capsular bag of the eye, relative to an optical axis of the eye. The method further comprises determining an axial position parameter, which is representative of the axial position of the portion of the anterior surface, depending on the data. The method further comprises determining the at least one selection parameter for selecting the intraocular lens depending on the determined position parameter.

Method, ophthalmic measuring systems and computer-readable storage medium for selecting an intraocular lens

A system for performing a surgical procedure includes an OCT unit for scanning an object region volume with an OCT scanning beam and a control unit for setting the position of the object region volume. A surgical instrument having an effective section is arrangeable in an object region of the object region volume and is localizable in the object region volume with the OCT unit. A computer unit has a first computer program for determining the position of the effective section by processing scan information obtained by scanning the object region volume and a second computer program compares the scan information to reference data and provides a set value for the position of the effective section. The second computer program determines deviation information as to the spatial deviation of the effective section from the set value.

Surgical system having an OCT device

Method, ophthalmic measuring system and computer-readable storage medium for selecting an intraocular lens

The invention relates to an optical system for examining an eye by means of optical coherence tomography. The OCT system is designed in such a way that at least a first and a second state of the optical system can be selectively set by controlling the variable optical unit. In the first state, the OCT measurement beam has a measurement focus at an object distance from the objective, wherein the object distance has a value between 50 millimeters and 400 millimeters. In the second state, the measurement beam has defocusing at the same object distance, wherein the defocusing corresponds to a distance of a virtual or real focus from a position of the object distance that is greater than 100 millimeters.

System for optical coherence tomography, comprising a zoomable kepler system

An optical filter system for florescence observation comprises an illumination light filter (I) and an observation light filter (O). The observation light filter has plural transmitting regions (D,D) allowing fluorescent light to traverse the observation light filter. Blocking regions (S,S) separate the transmitting regions. The illumination light filter has transmitting regions (D,D) where the observation light filter has a corresponding blocking region. The illumination light filter has blocking regions (S,S) where the observation light filter has a corresponding transmitting region. The plural transmitting regions of the illumination light filter hallow for an improved color impression in the normal light observation.

Optical filter system and fluorescence observation system

A surgical microscope for imaging structures of an eye includes: a front optical unit, an illumination device which has an illumination-radiation-emitting illumination source and which illuminates the retina of the eye with an illumination spot via an illumination beam path which extends through the front optical unit, a camera and an adjustable camera optical unit disposed upstream thereof, an imaging beam path which extends through the front optical unit and the camera optical unit, and a control device which controls the camera optical unit and sets the latter in such a way that the retina of the eye in the region of the illumination spot is imaged on the camera. The control device varies a focusing state of the camera optical unit and, as a result thereof, records a plurality of images of the retina in the region of the illumination spot, the images being focused in different depth planes, and establishes a refractive value of the eye from these images.

Surgical microscope

The present disclosure relates to a system for examining an eye. The system comprises a microscopy system for generating an image plane image of an object region. An OCT system of the system is configured to acquire OCT data from the object region which reproduce the object region in different stress states. A data processing unit of the system is configured to determine at least one value of a stress-dependent parameter, depending on the OCT data. The system generates an output image that is dependent on the image plane image and is furthermore dependent on the stress-dependent parameter.

System for eye examination by means of stress-dependent parameters

An ophthalmology microscopy system for observing fluorescence comprises an imaging system and an illumination system. The imaging system provides at least one optical imaging path producing a magnified multi-dimensional image of an object disposable in a focal plane of the imaging system, and comprises at least one optical observation filter. The illumination system provides an illumination beam path intersecting the focal plane of the imaging system at a variable angle of less than 90&#xb0;. The microscopy system comprises first and second operating states. In the first operating state, radiation passing through the illumination beam path has at least in a section along the illumination beam path a spectrum free of a pass band of the observation filter. In the second operating state, radiation passing through the illumination beam path has a spectrum having a bandwidth of at least 200 nm in a range from 380 nm to 780 nm.

Microscopy system for observing fluorescence in ophthalmology

An illumination system of a microscopy system comprises an actuator configured to change an angle of an illumination light beam and a mirror assembly, which is selectively positionable into the beam path of the illumination light beam. The mirror assembly may comprise an actuator configured to change an orientation of a mirror with respect to another mirror.

Stereo microscope system

A method of visualizing objects using an optical system including an OCT system configured to obtain OCT data from voxels within a first volume having a first lateral extent includes obtaining position data indicative of a position of a predetermined portion of a movable instrument relative to the optical system and determining a first set of voxels from the voxels of the first volume based on the determined position such that at least 80% of the first set of voxels is located within a second volume having a second lateral extent with a size at least half the size of the first lateral extent. The method also includes obtaining OCT data of the first set of voxels, visualizing a representation of the OCT data of the first set of voxels, and repeating the steps of the method at a first repetition rate higher than 5 times per second.

Growing community of inventors

Unterschneidheim, Germany

Holger Matz