Basf Se Corporation

Evolva Sa

Holger Hartmann

Markus Pompejus

Zheyuan Guo

Qingzhao Wang

Shakir Siraj Ratani

Hartwig Schröder

Hartwig Schroeder

Oskar Zelder

Klaus Ditrich

Michael Breuer

Stefan Haefner

Birgit Hoff

Andrea Molt

Stefan Jenewein

Max Fabian Felle

Kerstin Hage

Nico Boehmer

Andreas Thywissen

Jakob Weber

Karsten Koerber

Michael Naesby

Christophe Folly

Markus Schwab

Curt Aimé Friis Nielsen

Anaelle Hatsch

Rüdiger Reingruber

Rüdiger Reingrubber

The present invention generally relates to the field of fermentation technology and microorganisms useful for such fermentations. The invention also relates to materials including nucleic acids and proteins useful for altering fermentation characteristics of microorganisms, and to microorganisms comprising such nucleic acids and/or proteins.

Modified bidirectional catalase promoter from bacillus

Method of increasing catalase expression or activity

The present invention relates to a method of producing a recombinant polypeptide a filamentous fungus which is genetically modified to decrease or eliminate the activity of cellulase regulator 2 (CLR2) and to express said recombinant polypeptide. The method further relates to a filamentous fungus, which is genetically modified to decrease or eliminate the activity of CLR2 and the use of this filamentous fungus in the production of a recombinant polypeptide.

Method of producing proteins in filamentous fungi with decreased CLR2 activity

The present invention relates to a recombinant nucleic acid molecule, a recombinant microorganism, to a method for producing alanine and to the use of the recombinant nucleic acid molecule or the recombinant microorganism for the fermentative production of alanine.

Recombinant microorganism for improved production of fine chemicals

The present invention relates to a method of producing a recombinant polypeptide in a filamentous fungus which is genetically modified to decrease or eliminate the activity of cellulase regulator 1 (CLR1) and to express the recombinant polypeptide. The method further relates to a filamentous fungus, which is genetically modified to decrease or eliminate the activity of CLR1 and to the use of this filamentous fungus in the production of a recombinant polypeptide.

Method of producing proteins in filamentous fungi with decreased CLR1 activity

Recombinant microorganism for improved production of fine chemicals The present invention relates to a recombinant nucleic acid molecule, a recombinant micro-organism, to a method for producing alanine and to the use of the recombinant nucleic acid molecule or the recombinant microorganism for the fermentative production of alanine.

Microorganisms and processes for the recombinant manufacture of clavine-type alkaloids such as cycloclavine, festuclavine, agroclavine, chanoclavine and chanoclavine aldehyde, as well as polypeptides, polynucleotides and vectors comprising such polynucleotides which can be applied in a method for the manufacture of clavine-type alkaloids are provided.

Genes and processes for the production of clavine-type alkaloids

The invention pertains to the field of production of natural products and, in particular, in the field of production of cornexistin and hydroxycornexistin. It provides polynucleotides encoding polypeptides involved in the biosynthesis of cornexistin and hydroxycornexistin as well as vectors and recombinant microorganisms comprising such polynucleotides. Also provided are methods for the production of natural products, in particular methods for the production of cornexistin and hydroxycornexistin, using such polynucleotides and polypeptides encoded therein, as well as vectors and recombinant microorganisms comprising such polynucleotides and polypeptides.

Gene cluster for biosynthesis of cornexistin and hydroxycornexistin

The invention pertains to the field of production of natural products and, in particular, in the field of production of cornexistin and hydroxycornexistin. It provides polynucleotides encoding polypeptides involved in the biosynthesis of cornexistin and hydroxycornexistin as well as vectors and recombinant microorganisms comprising such polynucleotides. Also provided are methods for the production of natural products, in particular methods for the production of cornexistin and hydroxycornexistin, using such polynucleotides and polpeptides encoded therein, as well as vectors and recombinant microorganisms comprising such polynucleotides and polypeptides.

Growing community of inventors

Schwetzingen, Germany

Holger Hartmann