Quantum Magnetics, Inc.

Hoke Smith Trammell, Iii

Sankaran Kumar

William Frank Avrin

Peter Victor Czipott

Walter N Freeman

A probe instrument using room-temperature sensor(s) that can measure variations in magnetic susceptibilities. The instrument has sufficient resolution to monitor paramagnetic materials in a human body, such as iron in a human liver, by noninvasively examining patients with iron-overload diseases. The instrument includes room temperature magnetic sensors, and detects the sample, that is, the tissue response to an alternating current field applied by an applied field coil. The applied field coil dimensions are chosen so that the applied field is optimized for maximum response from the liver while minimizing the effects due to the overlying abdominal tissue and at the same time not unduly increasing the sensitivity of the instrument to the lung. To overcome variations in the sensor output due to fluctuations in the applied field, change in the ambient temperature and mechanical relaxation of the instrument, the sensor-sample distance is modulated. The detector assembly is oscillated while the examined patient remains stationary. An improved water-bag technique is employed to eliminate background tissue response. The detector assembly forms part of a probe instrument for performing noninvasively the paramagnetic concentration of a patient.

Simplified water-bag technique for magnetic susceptibility measurements on the human body and other specimens

An apparatus for and a method of measuring material thickness with magnetics. The thickness monitoring system includes a thickness monitor, a probe, and a target. In a preferred embodiment, the probe is positioned on one side of an article for which the thickness is to be determined. The target is positioned on the opposite side of the article from the probe. The probe includes an excitation coil, a field compensation coil, and a magnetic sensor. The method includes energizing the excitation coil to excite a response from the target, compensating for the effect of the excitation coil on the magnetic sensor, measuring the response of the target with the magnetic sensor, and determining the thickness of the article from the measured response. The preferred mode of energizing the excitation coil is with an AC waveform; however DC, multi-frequency AC, or a combination of AC and DC waveforms may be used.

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San Diego, CA, United States of America

Hoke Smith Trammell, Iii