Applied Biosystems, LLC

Life Technologies Corporation

Hock Lai Khoo

Hon Siu Shin

Mark T Reed

Wolfgang Heimberg

Jew Kwee Ngui

Lim Hi Tan

Yang Hooi Kee

Ui Leng Soh

Ching Ong Lau

Hou Siu Shin

Hon Siu No 23 Tampines Street 34 03-11 Shin

An apparatus and method for thermal cycling including a pasting edge heater. The pasting edge heater can provide substantial temperature uniformity throughout the retaining elements during thermal cycling by a thermoelectric module.

Pasting edge heater

The invention relates to a device for carrying out of chemical or biological reactions with a reaction vessel receiving element for receiving a microtiter plate with several reaction vessels, wherein the reaction vessel receiving element has several recesses arranged in a regular pattern to receive the respective reaction vessels, a heating device for heating the reaction vessel receiving element, and a cooling device for cooling the reaction vessel. The invention is characterized by the fact that the reaction vessel receiving element is divided into several segments. The individual segments are thermally decoupled from one another, and each segment is assigned a heating device which may be actuated independently of the others. By means of the segmentation of the reaction vessel receiving element, it is possible for zones to be set and held at different temperatures. Because the reaction vessel receiving element is suitable for receiving standard microtiter plates, the device according to the invention may be integrated in existing process sequences.

Device for carrying out chemical or biological reactions

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Singapore, Singapore

Hock Lai Khoo