Korea Research Institute of Bioscience and Biotechnology

Ho Yong Park

Tae-Sook Jeong

Kwang Hee Son

Tae Sook Jeong

Jong-Min Han

Myung-Sook Choi

Hyun-Woo Oh

Woo-Song Lee

Doo-Sang Park

Eun Young Suh

Ki-Duk Kim

Dong Ha Shin

Sang Ho Choi

Ki Hun Park

Dong-Ha Shin

Woo Song Lee

Hyung-Jae Jeong

Sung Uk Kim

Jae Sun Moon

Han-Young Cho

Soo Yong Kim

Hyeon-Seon Ji

Ingyu Hwang

Rosales Ovares Kattia

Byoung-Keun Park

Zamora Villalobos Nelson

Hua Li

Seungeun Kim

Hwa Lee

The present invention relates to a cosmetic composition for preventing skin aging and reducing skin wrinkles containing an extract of-The cosmetic composition has an excellent antioxidant effect and exhibits the effect of inhibiting collagenase overexpression and increasing collagen gene expression, and thus can be effectively used for the purposes of preventing skin aging and reducing skin wrinkles.

Cosmetic composition for preventing skin aging and reducing skin wrinkles, comprising Viburnum stellato-tomentosum extract

A composition for prevention or treatment of metabolic syndrome or for antioxidation includes black soybean leaf extracts and flavonol glycoside compounds isolated thereof as active ingredients. It has been confirmed that the black soybean leaf extracts and the flavonol glycoside compounds isolated thereof effectively inhibit &#x3b1;-glucosidase activity; LDL oxidation and DDP-4; have excellent DPPH radical scavenging activity; inhibitory activity of reactive oxygen species (ROS) accumulation; effectively promote insulin secretion; regulate the expression of major genes; have an excellent ability to reduce a waist/hip circumference ratio; decrease the concentrations of plasma free fatty acid and plasma triglyceride; increase the concentration of plasma HDL-cholesterol; decrease an atherogenic index; increase erythrocyte catalase, SOD and GR activities; decrease erythrocyte lipid peroxide TBARS; decrease the concentrations of inflammatory cytokines MCP-1 and PAI-1, and resistin; and increase the concentration of plasma adiponectin.

Composition for prevention or treatment of metabolic syndrome or for antioxidation containing black bean leaf extracts and flavonol glysosides isolated therefrom as active ingredients

The present invention relates to compositions for preventing and treating obesity, hyperlipidemia, atherosclerosis, fatty liver, diabetes or metabolic syndrome containing extracts ofleaves or fractions isolated from the same.

Compositions for preventing and treating obesity, hyperlipidemia, atherosclerosis, fatty liver, diabetes or metabolic syndrome containing extracts of glycine max leaves or fractions isolated from the same as an active ingredient

The present invention relates to novel iturin biosynthesis genes, and uses thereof. More specifically, the present invention provides novel iturin biosynthesis genes, wherein the iturin biosynthesis genes were cloned fromsubsp.ATCC 55079, the base sequence was determined after checking whether the cloned genes are iturin biosynthesis genes or not, and it was ascertained that the identified genes are novel genes different from the reported gene by comparing the base sequences with that of the reported gene, and uses thereof.

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The present invention relates to a composition for the prevention and treatment of cardiovascular diseases containing the novel quinoline compound, the centipede extracts or compounds isolated from the extracts. The novel quinoline compound, the centipede extracts or a quinoline compound and a phenol compound isolated from the extracts of the invention exhibit excellent LDL-antioxidant activity, ACAT inhibiting activity, and anti-inflammatory activities, so that they can be included as an effective ingredient in a composition for the prevention and treatment of cardiovascular disease including hyperlipidemia, atherosclerosis, coronary heart disease, and myocardial infarction mediated by LDL-oxidation, cholesteryl ester synthesis and accumulation, and inflammation.

Quinoline compound, and composition containing centipede extract or compounds isolated therefrom for prevention and treatment of cardiovascular disease

The present invention relates to agenus microorganism and microbial insecticide for controlling the soil pests using the same, more particularly to agenus microorganism having insecticidal activity to soil pests and a microbial insecticide for controlling the soil pests containing the same. Since the microbial insecticide of the present invention shows excellent insecticidal activity to harmful soil pests, it can effectively be used as a environment-compatible insecticide to prevent the soil pests from farmland crops.

The present invention relates to a novel fungus ofgenus and a method for controlling soil pests using the same, more particularly to a novelHY-2 and a microbial insecticide comprising the same and a method for controlling soil pests using the same. TheHY-2 can effectively be used to control the soil pests such as Scarabaeidae.

Growing community of inventors

Daejion, South Korea

Ho Yong Park