Korea Advanced Institute of Science and Technology

Lab To Market Inc.

E1 Biotech Co., Ltd.

Bisinformatix, Inc.

Seebio Inc.

Ho Nam Chang

Yong Keun Chang

Sang Yup Lee

Je Hwan Chang

Seong Jin Lim

Sung-Keun Rhee

Jung Hyun Sung

Woo-Gi Lee

Pyung Cheon Lee

Sun Hoon Kwon

Woo Gi Lee

Tae Yong Kim

Bong Hyun Chung

Hyohak Song

Do-Yun Kim

Dong Won Choi

Yoon Seok Chang

Ik Keun Yoo

Yeu-Chun Kim

Bo-Kyung Choi

Moon-II Kim

Kwonsu Jung

Charles Seo

Chul-Hee Ryu

Gwon Woo Park

Nam Uook Kim

The present invention relates to a method for concentrating, with low energy, a solute-containing solution in a state of multiple-no osmotic pressure difference (M(multiple)−Δπ=0 RO), and, more specifically, to a method for concentrating, with low energy, an solute-containing solution intended to be concentrated, as a low pressure in a state of multiple-no osmotic pressure difference. The method for concentrating a solution containing a solute at a low pressure in a state of multiple-no osmotic pressure difference, of the present invention, consumes less energy, enables concentration to be performed until a saturated aqueous solution with a maximum solute concentration is obtained or the concentration of the solute becomes 100% even though an extraction solvent is not used, and does not require the use of an additional osmosis-inducing solution.

Method for concentrating aqueous solution with low energy by using reverse osmosis and forward osmosis in state in which multiple-no osmotic pressure difference is induced

The present invention relates to a method of concentrating an aqueous solution by low pressure under a zero osmotic pressure difference condition, and more particularly to a method of concentrating a solute-containing aqueous solution by low pressure under a zero osmotic pressure difference condition. When the method of the present invention is used, there are advantages in that energy consumption is low, and an aqueous solution can be concentrated until it can reach the maximum solute concentration or a solute concentration of 100%, without having to use an extraction solvent. In addition, there is an advantage in that the need to use a separate osmotic pressure draw solution is eliminated.

Method of osmotic pressure free reverse osmosis for enriching solute-containing solution to high concentration

The present invention relates to a method of concentrating an aqueous solution at low pressure under a zero osmotic pressure difference condition, and more particularly, to a method of concentrating an aqueous solution containing a solute to be concentrated, at low pressure under a zero osmotic pressure difference condition. The method of the present invention comprises the steps of: (a) discharging water of a solute-containing aqueous solution to be concentrated, from a reverse osmosis separator to the outside, and transferring the concentrated aqueous solution to a zero osmotic pressure difference concentrator; (b) further concentrating the concentrated aqueous solution using the zero osmotic pressure difference concentrator comprising a feed chamber and a draw chamber, which are separated from each other by a reverse osmosis membrane or a forward osmosis membrane; and (c) recovering the solute and water from the aqueous solution further concentrated in the zero osmotic pressure difference concentrator. When the method of concentrating the aqueous solution at low pressure under the zero osmotic pressure difference condition is used, the aqueous solution can be concentrated to the maximum saturation concentration of a solute or a solution concentration of 100% using a reduced amount of energy without having to use an extraction solvent. In addition, there is an advantage in that a separate osmosis draw solution does not need to be used.

Method for concentrating aqueous containing solute into high concentration by hydraulic-membrane process under no difference in osmotic pressure

A method for developing a culture medium using genome information and in silico analysis. In one implementation, the method involves developing a minimal synthetic medium, including the steps of constructing a metabolic network using genome information of prokaryotic cell or eukaryotic cell, selecting components of the minimal synthetic medium removing any one among external metabolites from the constructed metabolic network and conducting metabolic flux analysis using in silico simulation, and determining a final culture medium by actual culture.

[object Object]

Disclosed is an on-site treatment method of food waste generated from multi-unit dwellings and institutional food service facilities, by transporting wastewater-containing food waste to a separation chamber by use of domestic wastewater or an additional transporter; separating the transported food waste to wastewater and food waste; and treating the separated wastewater in a sewage disposal plant, and the separated food waste using disposal equipment. Such food waste can be treated even using disposal equipment of small capacities, due to separation of wastewater and food waste, compared to disposal equipment of large capacities required for treating wastewater and food waste together. Also, the quality of the separated wastewater is better than the conventional quality of wastewater, and thus loads of the sewage disposal plant can be efficiently decreased.

On-site treatment method of food waste generated from collective residence or institutional food service facilities

A novel microorganism capable of producing organic acids,sp. 55E, and a process for producing organic acid through anaerobic and aerobic incubation using the novel microorganism are provided. The method of producing an organic acid using the microorganism involves incubatingsp. 55E with Accession Number KCTC 0769BP in a medium under anaerobic or aerobic conditions and obtaining an organic acid from the medium.sp. 55E produces succinic acid, lactic acid, and formic acid under anaerobic conditions saturated with CO, and succinic acid, lactic acid, acetic acid, and formic acid under aerobic or Nanaerobic conditions.sp. 55E is a facultative anaerobe tolerant of oxygen. Thus, the use ofsp. 55E in producing organic acids can eliminate a problem of process instability, which would occur by the presence of oxygen in a fermentation process of producing organic acids using an obligate anaerobic microorganism.

Organic acid producing microorganism and process for preparing organic acids employing the same

The present invention provides a method for manufacturing organic acid by high-efficiency fermentation, which comprises the steps of continuous culture of organic acid bacteria and collection of organic acid produced from the culture employing a cell-recycle multiple-stage continuous fermentor with serially connected fermentors, each of which comprises a fermentor containing a ferment container, temperature controller, stirrer, and pH controller; pumps for efflux-circulation of media from the fermentor; and, cell separator for separation and circulation of media from the pumps. According to the present method, the high-concentration lactic acid of 90 g/L can be produced with the high productivity of 50 g/L/h, which can reduce the facility cost and production cost in the bulk manufacturing process. In addition, the present invention can be effectively applied to the production of other organic acids such as acetic acid, formic acid, citric acid, malic acid, maleic acid, fumaric acid, and succinic acid, which show the end-product inhibition.

Method for manufacturing organic acid by high-efficiency continuous fermentation

The present invention provides to a method for removing nitrogen and phosphorous in wastewater simultaneously from wastewater by employing fermentation broth obtained by anaerobic fermentation of organic solid wastes. The method for removing nitrogen and phosphorous in wastewater of the invention comprises the steps of subjecting organic waste material to anaerobic fermentation at 30 to 40&deg; C. for 2 to 4 days by using anaerobic sludge to obtain fermentation broth; and, adding the fermentation broth to a sequencing batch reactor with alternating anaerobic-aerobic-anoxic cycles under anaerobic and anoxic conditions in a separate manner. In accordance with the present invention, nitrogen in the influent wastewater can be removed more than 95% in total and phosphorous concentration can be kept below 1 ppm regardless of the concentration of organic materials in the influent wastewater. Further, the present method requires no extra pretreatment steps or chemicals which are essential to remove residual ammonia nitrogen in the prior art systems, and lowers the overall cost for wastewater treatment due to the usage of organic waste materials.

Method for removing nitrogen and phosphorous in wastewater

The present invention relates to Gordona sp. CYKS1 (KCTC 0431BP) capable of selective removal of organically bound sulfurs from carbonaceous fossil fuel such as petroleum and coal by cleaving bonds between carbon and sulfur atoms in the said sulfur-containing organic compounds, and a method for biological desulfurization using this strain at the room temperature and atmospheric pressure. Since Gordona sp. CYKS1 (KCTC 0431BP) utilizes various organic sulfur compounds in fossil fuel besides dibenzothiophene as a sole sulfur source, the method for biological desulfurization employing the Gordona strain has advantages over the conventional chemical methods as followings: The desulfurization can be carried out at a mild condition; the cost for installation and operation of equipments can be reduced; and, the desulfurization of highly complex organic sulfur compounds can be realized.

Gordona sp. CYKS1 (KCTC 0431BP) capable of desulfurizing fossil fuel containing organic sulfur compounds

The present invention relates to Nocardia sp. CYKS2 (KCTC 0432 Br) capable of selective removal of organically bound sulfurs from carbonaceous fossil fuel such as petroleum and coal by cleaving bonds between carbon and sulfur atoms in the said sulfur-containing organic compounds, and a method for biological desulfurization using this strain at the room temperature and atmospheric pressure. Since Nocardia sp. CYKS2 (KCTC 0432 Bp) utilizes various organic sulfur compounds in fossil fuel besides dibenzothiophene as a sole sulfur source, the method for biological desulfurization employing the Nocardia strain has advantages over the conventional chemical methods as followings: The desulfurization can be carried out at a mild condition; the cost for installation and operation of equipments can be reduced; and, the desulfurization of highly complex organic sulfur compounds can be realized.

Norcardia sp. CKYS2 ((KCTC 0432BP) capable of desulfurizing fossil fuel containing organic sulfur compounds

Aspergillus niger B60 was immobilized in a dual hollow fiber bioreactor to produce citric acid continuously. The fungi proliferated well in the interstitial region formed by a parallel arrangement of three microporous polypropylene hollow fibers contained within a silicone tube. Excessive fungal cell growth could be controlled by supplying a nitrogen-deficient medium at the production stage, and also uniform cell distribution in the reactor could be obtained by changing the direction of medium flow. With pure oxygen aeration and nitrogen-deficient medium, volumetric productivity reached 1.62 g/l.h at a residence time of 4.02 h, which corresponded to a 27-fold increase over that of shake-flask fermentation. When the residence time was increased to 20.1 h, citric acid at a concentration of 26 g/l was continuously produced, with a yield of 80-90% and a volumetric productivity of 1.3 g/l.h. This represents a significant improvement in final concentration, yield and the volumetric productivity over the equivalent values of the corresponding batch formentation, which were 18 g/l, 40% and 0.06 g/l.h, respectively.

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Seoul, South Korea

Ho Nam Chang