Fujifilm Corporation

Hiyoku Nakata

Ken Kawata

Yohei Kubo

Takashi Tamura

Saisuke Watanabe

Hidenobu Kuniyoshi

Shinsuke Mizumoto

Yasutaka Baba

Hideyasu Fujiwara

Shinji Hagiwara

Mari Yamamoto

Makoto Ando

Kousuke Watanabe

Yoshinori Kanazawa

Kazuhei Kaneko

Daisuke Terada

Akiko Hattori

Takuya Matsumoto

Tomoyuki Mashiko

Yuichiro Sato

Kimihiko Sato

Atsushi Tatsugawa

Hideki Kurihara

Shuhei Osaka

Akihiro Asakura

Keiko Makita

Tatsuya Nitabaru

Hidehiko Tanaka

Provided are any one of the following fluorescent compounds and a fluorescent labeled biological substance having this fluorescent compound. However, in a case where the ring βand the ring βare a 6-membered ring, and Land Lare an arylene group, Ris not an aryl group substituted with a linear alkyl group having 18 or more carbon atoms. In addition to the regulation of the ring β, the ring β, L, and L, in a case where Rhas a substituent having a dipyrromethene boron complex structure, the dipyrromethene boron complex structure has a structure in which a dipyrromethene skeleton is coordinately bonded to a boron atom in the tridentate or tetradentate coordination.

Fluorescent compound and fluorescent labeled biological substance using the same

There is provided a morpholine derivative represented by General Formula [1A] or a salt thereof  (In the formula, a ring A represents a ring represented by General Formula [I]; * represents a bonding position; Zrepresents CH or the like; Zrepresents CRor the like; Rrepresents a hydrogen atom or the like; Xrepresents CHRor the like; Rrepresents a hydrogen atom or the like; Xrepresents CHor the like; Rand Rare the same as or different from each other, and each of Rand Rrepresents a hydrogen atom or the like; R, R, and Rare the same as or different from each other, and each of R, R, and Rrepresents a hydrogen atom, NRR, or the like; and each of Rand Rrepresents a hydrogen atom, a Calkyl group which may have a substituent, or the like).

Morpholine derivative or salt thereof

A compound represented by following formula (I): A-L-{D-(E)-D-(B)&#x2014;Z&#x2014;R}. In the formula, A represents a p-valent chain or cyclic residue; L represents a single bond or a divalent linking group; p represents an integer of 2 or more; Drepresents a carbonyl group (&#x2014;C(&#x2550;O)&#x2014;) or a sulfonyl group (&#x2014;S(&#x2550;O)&#x2014;); Drepresents a carbonyl group (&#x2014;C(&#x2550;O)&#x2014;), a sulfonyl group (&#x2014;S(&#x2550;O)&#x2014;), a carboxyl group (&#x2014;C(&#x2550;O)O&#x2014;), a sulfonyloxyl group (&#x2014;S(&#x2550;O)O&#x2014;), a carbamoyl group (&#x2014;C(&#x2550;O)N(Alk)-) or a sulfamoyl group (&#x2014;S(&#x2550;O)N(Alk)-); E represents a divalent group; and R represents a hydrogen atom, a substituted or non-substituted Cor longer alkyl group, a perfluoroalkyl group or a trialkylsilyl group.

Compounds useful in various fields of a lubricant

[Problem] Provided is a novel lubricant composition that is useful as a material of a lubricating layer of a magnetic recording medium. [Means for Resolution] The lubricant composition contains at least one kind of compound represented by the following Formula (1). In the formula, X represents a cyclic group that may be substituted, and Y represents a single bond or a linking group having a valency of 2 or more. Here, at least one of X and Y includes 1 or more polar groups such as a hydroxyl group; Z represents a linking group having a valency of 2 or more and constituted with a carbon atom (C), a fluorine atom (F), and 1 or 2 kinds of arbitrary atoms (here, a hydrogen atom is excluded); n represents a real number of 1 to 10; m represents a real number of 0 to 1; and s and t independently represent a real number of 1 or greater.XYZ&#x2014;CFH]]&#x2003;&#x2003;(1)

Lubricant composition and use thereof

The object of the present invention is to provide a compound and a pharmaceutical composition having excellent Syk inhibitory activity. According to the present invention, a nicotinamide derivative represented by the following formula (I) or a salt thereof is provided, wherein (wherein R, R, R, n, and Xhave the same definitions as those described in the specification), and Ris a pyridyl, indazolyl, phenyl, pyrazolopyridyl, benzisoxazolyl, pyrimidinyl, or quinolyl group, each of which optionally has at least one substituent.

Nicotinamide derivative or salt thereof

An object of the present invention is to provide to a compound and a pharmaceutical composition, which have excellent Syk-inhibitory activity. The present invention provides a nicotinamide derivative represented by the following formula (I) (wherein Rrepresents a halogen atom; Rrepresents a Calkyl group, a Calkenyl group, a Calkynyl group, a Ccycloalkyl group, an aryl group, an ar-Calkyl group or a heterocyclic group, each optionally having at least one substituent; Rrepresents an aryl group or a heterocyclic group each optionally having at least one substituent; and Rand Reach independently represent a hydrogen atom; and Rand Rmay form a cyclic amino group optionally having at least one substituent together with the nitrogen atom to which they bind) or a salt thereof, and a pharmaceutical composition for use in the treatment of a Syk-related disease which comprises the nicotinamide derivative or a salt thereof.

To provide a novel compound. It is disclosed a compound represented by following formula (I): A-L-{D-(E)-D-(B)&#x2014;Z&#x2014;R}. In the formula, A represents a p-valent chain or cyclic residue; L represents a single bond or a divalent linking group; p represents an integer of 2 or more; Drepresents a carbonyl group (&#x2014;C(&#x2550;O)&#x2014;) or a sulfonyl group (&#x2014;S(&#x2550;O)&#x2014;); Drepresents a carbonyl group (&#x2014;C(&#x2550;O)&#x2014;), a sulfonyl group (&#x2014;S(&#x2550;O)&#x2014;), a carboxyl group (&#x2014;C(&#x2550;O)O&#x2014;), a sulfonyloxyl group (&#x2014;S(&#x2550;O)O&#x2014;), a carbamoyl group (&#x2014;C(&#x2550;O)N(Alk)-) or a sulfamoyl group (&#x2014;S(&#x2550;O)N(Alk)-); E represents a divaltn group; and R represents a hydrogen atom, a substituted or non-substituted Cor longer alkyl group, a perfluoroalkyl group or a trialkylsilyl group.

Compound

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Ashigarakami-gun, Japan

Hiyoku Nakata