Tohoku University

Japan Aviation Electronics Industry, Limited

Mochida Pharmaceutical Co., Ltd.

Hitoshi Shiku

Tomokazu Matsue

Atsushi Suda

Ryota Kunikata

Kosuke Ino

Mayuko Terauchi

Noriko Taira

Kumi Inoue

Takahiro Ito

Isamu Uchida

Miho Ikegawa

Kentaro Ito

A hydrogel is formed by a reaction which is induced, in an electrolytic solution, by an electrode product electrochemically generated by electrodes installed in the electrolytic solution. An apparatus including an electrolytic tank with a bottom surface on which a two-dimensional array of working electrodes is provided and a counter electrode installed in the electrolytic tank is prepared. An electrolytic solution containing a dissolved substance that causes electrolytic deposition of a hydrogel is housed in the electrolytic tank. By applying a predetermined voltage to one or more selected working electrodes of the two-dimensional array, a hydrogel with a two-dimensional pattern corresponding to the arrangement of the selected working electrodes is formed.

Method of electrochemically producing hydrogel, method of producing hydrogel with pattern formed of cells, hydrogel production apparatus, and transducer

Provided are a device and a method for rapidly and simply detecting endotoxin without using an expensive reagent. The endotoxin detection device includes: a region containing an electrolyte solution; a partitioning member that partitions the region into two compartments such that the two compartments are in communication via a nanopore; a first electrode that is disposed in a first compartment; a second electrode that is disposed in a second compartment and is electrically connected to the first electrode; an electrolyte solution flow generating means that causes electrolyte solution in the first compartment to move to the second compartment via the nanopore; an application means that applies voltage between the first electrode and the second electrode; and a monitoring means that monitors current.

Endotoxin detection device and endotoxin detection method

An electrode chip including one auxiliary cell and a plurality of measurement cells on a substrate, where the auxiliary cell includes a reference electrode, a counter electrode, and an auxiliary cell-side working electrode, the measurement cell includes a driving electrode and a measurement cell-side working electrode, and the auxiliary cell-side working electrode and the measurement cell-side working electrode are electrically connected.

Electrode chip

An analyte and a reactant 3 that reacts with the analyte either directly or indirectly are allowed to react with each other on the analytical areas A of a substrate 1 and signals originating from the reaction are detected. In at least a signal detection step, either a signal generation-related portion 4x or a detector is provided in a portion that is opposed to the substrate 1 and high and low areas are formed in either the substrate 1 or the opposed portion or both in such a manner that the distance from each analytical area A of the substrate to the opposed portion is shorter than the distance from each of the non-analytical areas B of the substrate to the opposed portion, whereby signals originating from the reaction in the analytical areas A will be detected at higher intensities than signals originating from the reaction in the non-analytical areas B. The analyte can be quantitatively or qualitatively analyzed on the analytical areas of the substrate in high precision with reduced effects from the non-analytical areas of the substrate. Simultaneous analysis of multiple samples or simultaneous analysis for multiple items can also be accomplished with a simple sensor configuration.

Analytical method and device for precise analysis with a simple sensor

Growing community of inventors

Sendai, Japan

Hitoshi Shiku