Tdk Corporation

Chugai Seiyaku Kabushiki Kaisha

Fujisawa Pharmaceutical Company, Ltd.

Hino Motors, Ltd.

Honda Giken Kogyo Kabushiki Kaisha

The Furukawa Electric Co., Ltd.

Kobelco Construction Machinery Co., Ltd.

Sumco Corporation

Dowa Eco-system Co., Ltd.

Hitoshi Sasaki

Syun Ashizawa

Satoshi Sugimoto

Mineo Niwa

Yoshimasa Saito

Daisuke Kameoka

Toru Yoshizawa

So Yamaguchi

Takahiro Banzai

Megumi Numata

Hiroko Murata

Masakazu Kobayashi

Naoka Hironiwa

Shingo Tsujihama

Masako Hayashi

Jouji Notani

Tomoyuki Igawa

Yoichiro Yamazaki

Yoshihiro Sato

Sadahiro Kato

Yoshihiro Honma

Masazumi Arata

Hiroshi Miwa

Kunihiko Kawasaki

Daisuke Urabe

Masayuki Iwami

Yoshinori Ishii

Yuki Niiyama

Yohei Tadaki

Masaaki Shoji

Yasuhiko Kitajima

Shigemitsu Nakabayashi

Yusuke Sawada

Kunio Oda

Yoshimitsu Satoh

Shaw Nishizawa

Chihiro Nishikawa

Koji Shimura

Shinya Ootomo

Ryoei Watanabe

Hiroki Hashimoto

Yoshiyuki Takanashi

Takuro Kugimiya

Atsushi Saeki

Riku Umeki

Tatsuya Yodose

Fumino Hasegawa

Shigenori Yoshimi

Akiyoshi Shimizu

Osamu Kurihara

Syunji Kuragaki

Yoshihiko Koshiishi

Miyoshi Yumiza

Takashi Ishii

The present invention relates to stable antibody-containing solution formulations in which aggregate formation of Emicizumab (ACE910) which is a bispecific antibody functionally substituting for FVIII, is suppressed. Specifically, the present invention relates to the above-mentioned antibody-containing solution formulations of pH 4.5 to 6.5 that contain the aforementioned bispecific antibody at 20 to 180 mg/mL, 10 mM to 40 mM histidine-aspartate buffer, Poloxamer 188 at 0.2 to 1 mg/mL, and 100 mM to 300 mM arginine.

Antibody-containing preparation

Provided is a sorting method for valuable resources, including a thermal treatment step of thermally treating a target containing valuable resources, to melt aluminum and separate a melt, a pulverizing step of pulverizing a thermally treated product remaining after the melt is separated, to obtain a pulverized product, a magnetic sorting step of sorting the valuable resources from the pulverized product by a magnetic force, and a wind force sorting step of sorting one valuable resource from another valuable resource in the valuable resources by a wind force.

Separation method for valuable resources

There is provided a camera installation structure for inside of operation room that can obtain a camera image with reduced shake to enable remote operation and hardly obstructs rear visual field in a case where an operator boards a working machine. A camera installation structureincludes an operation seat, a scaffold memberdisposed in a rear space, and mounting portions for mounting the scaffold member. The scaffold memberincludes a plurality of shelves, and, a camerainstalled on the fourth shelf, and mounting brackets. In a state where the mounting brackets are mounted on the mounting portions, a lensof the camerais disposed at a height position corresponding to a height of eyes of an operator in a case where the operator sits on the operation seat

Camera installation structure for inside of operation room

In one non-limiting embodiment, the present disclosure relates to lyophilized formulations containing an IL-31 antagonist (for example, an anti-IL-31RA antibody) as an active ingredient, the lyophilized formulations further containing arginine and/or a salt thereof and sucrose and/or trehalose. In another non-limiting embodiment, the present disclosure relates to solution formulations containing an IL-31 antagonist as an active ingredient, the solution formulations further containing arginine and/or a salt thereof. In other non-limiting embodiments, the present disclosure relates to methods for stabilizing an antibody (for example, an anti-IL-31RA antibody) in an antibody-containing formulation, methods for suppressing antibody aggregation (aggregate formation) in an antibody-containing formulation, and methods for reducing components with charge heterogeneity in an antibody-containing formulation, the methods being characterized in that the formulation is prepared to contain arginine and/or a salt thereof, and/or sucrose and/or trehalose.

Anti-IL-31RA antibody-containing formulations

A coil device includes a main core and a sub core. The main core includes a middle leg for winding a coil body and an outer leg connected with the middle leg via a base portion. The sub core is disposed to face the base portion across the middle leg. A gap between the middle leg and the sub core is wider than that between the outer leg and the sub core.

Coil device

Methods of administering anti-IL31A antibody-containing formulations

A coil component including a first conductive plate part formed with a first coil pattern having a first opening, and a second conductive plate part formed with a second coil pattern having a second opening and disposed at a predetermined interval in the laminating direction with respect to the first conductive plate part. The first conductive plate part and the second conductive plate part are made of the same single plate and are integrally formed by a bent joining segment.

Coil component and coil device

Disclosed herein is a coil component that includes a conductor plate; and a magnetic core comprising a magnetic material having conductivity, the magnetic core having a through hole into which the conductor plate is inserted. The conductor plate includes: a metal element body having a body part positioned inside the through hole and a terminal part positioned outside the through hole; a metal film formed on the terminal part, the metal film comprising a metal material having a lower melting point than the metal element body; and an insulating film formed on a surface of the body part without the metal film interposed.

Coil component and manufacturing method thereof

Anti-IL31RA antibody-containing formulations

Rather than simply changing a component or module to be installed, a conveyance speed of a conveyance means for conveying a workpiece is modified in response to the specifications of a product when a product with specifications modified in part from common specifications of mass produced products is added to the mass produced products. Furthermore, a condition wherein the speed of the conveyance means is modified in accordance with specifications is displayed in real time such that a worker can identify the condition.

Assembly stand, assembly method, and process display device for article

A coil component having a core, first and second terminal electrodes provided on the core, and a conducting wire having a winding portion provided on the core and end portions electrically connected to the first and second terminal electrodes to provide first and second connecting portions. The core has one side surface at which the first and second connecting portions are provided. When viewing the one side surface, a wire portion in the winding portion extends in a first direction, and a wire portion extending from the second connecting portion extends toward the winding portion in a second direction. The first and second directions define an intersection angle of not more than 90 degrees.

Coil component and method for producing the same

Supplying work for many parts supplied for vehicle assembly is progressed toward one radiation center, and the supplied parts are assembled into one vehicle on a rotary-type assembly bed provided at the radiation center.

Assembly plant and assembly method for vehicle

A vertical semiconductor element comprises: an electro-conductive substrate; a GaN layer, as a nitride compound semiconductor layer, which is selectively grown as a convex shape on one surface of the electro-conductive substrate through a buffer layer; a source electrode as a first electrode formed on the GaN layer; and a drain electrode as a second electrode formed on another surface of the electro-conductive substrate.

Vertical type semiconductor device and manufacturing method of the device

A laminated inductor, as well as a method of manufacturing such a laminated inductor, are provided. The laminated inductor includes: a laminate; a pair of external electrodes arranged on the outer surfaces of the laminate respectively; and a coil, arranged within the laminate and formed by electrically connecting a plurality of strip-like conductor patterns. The conductor patterns have: a pair of broad faces, intersecting the lamination direction and mutually opposing; and peripheral side faces adjacent to the pair of broad faces and extending in the lamination direction. The peripheral side faces are concavo-convex faces, in which concave portions and convex portions are arranged in alternation in the lamination direction. The laminate enters into the concave portions of the peripheral side faces.

Laminated inductor and method of manufacture of same

A heat shielding memberthat thermally shields the periphery of a single crystalused in a Czochralski single crystal pulling device that pulls the single crystalfrom a meltthat is collected in a crucibleis disclosed. The heat shielding memberis provided with an approximately cylindrical main body portionarranged so as to surround the single crystalwith a lower end portion thereof extending to the vicinity of the melt, and an approximately annular bottom plate portionthat extends in the diameter direction from the bottom end portion of the main body portionto cover the melt. The bottom plate portionis attached to the main body portionin the state of being severed in the circumferential direction at at least one location. With this constitution it is possible to provide a heat shielding member with superior durability and a single crystal pulling device that employs the heat shielding member.

Heat shield member and single crystal pulling device

Growing community of inventors

Tokyo, Japan

Hitoshi Sasaki